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1520例上消化道出血病因和临床特点分析 被引量:45

Etiology and Clinical Characteristic of Upper Gastrointestinal Haemorrhage:Analysis of 1520 Cases
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摘要 目的研究近6年上消化道出血病因结构变化及临床发病特点。方法对2004~2009年1520例上消化道出血患者临床资料进行回顾性调查分析。结果男性多于女性,男∶女=3.4∶1,平均年龄52.8岁(14~102岁)。死亡38例(2.5%),52.6%死于大出血,47.4%死于非出血相关性疾病。上消化道出血前5位病因依次是消化性溃疡、食道胃底静脉曲张、胃癌、食管-贲门黏膜撕裂症和急性胃黏膜病变。大于60岁老年患者发病率呈上升趋势(31.1%、31.9%、32.4%、42.7%、38.1%、50.5%),胃癌是其首要病因(21.6%)。结论食道胃底静脉曲张发病率在不断上升,而急性胃黏膜病变发病率明显下降。随年龄增加,十二指肠溃疡发病率降低,胃溃疡和胃癌发病率增加。老年患者占上消化道出血患者比例越来越大,尤其合并严重基础疾病的老年患者有高危死亡风险,成为临床治疗的重点。 Objective To investigate the causes and clinical characteristic of upper gastrointestinal haemorrhage in the last 6 years.Methods A retrospective review of clinical records of 1 520 patients referred for UGIB between 2004-2009 was performed.Results The male patients were more than female patients,the ratio of male to female patients was 3.4∶1.The mean age was 52.8 years(14-102 years).38 patients died,52.6 percent died of hemorrhea,and 47.4 percent died of other causes.The first five causes of UGIB were peptic ulcer,gastroesophageal varices,gastric cancer,Mallory-Weiss tear and acute gastric mucosal lesion.The incidence of old patients had a tendency of increasing(31.1%,31.9%,32.4%,42.7%,38.1%,50.5%),gastric cancer was the most important cause(21.6%).Conclusion The morbility of gastroesophageal varices was rising,but acute gastric mucosal lesion.was descending.The DU patients decreased with age,but GU and gastric cancer increased.The percentage of old patients was more and more,especially old patients with severity comorbidity were high risk of death,who become emphasis of clincal therapy.
出处 《中华全科医学》 2010年第9期1079-1081,共3页 Chinese Journal of General Practice
关键词 上消化道出血 病因 发病率 Upper gastrointestinal haemorrhage Cause Morbility
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