摘要
目的探讨双相情感障碍患者认知功能与躁狂、抑郁、服药依从性及生活质量的相关性。方法对118例双相情感障碍患者采用蒙特利尔认知评估量表评估认知功能,比较不同认知功能水平患者汉密顿抑郁量表、贝克-拉范森躁狂量表、Morisky用药依从性问卷及世界卫生组织生存质量测定量表简表评分,分析认知功能与抑郁、躁狂、服药依从性以及生活质量的相关性。结果不同认知功能水平双相情感障碍患者汉密顿抑郁量表、贝克-拉范森躁狂量表、Morisky用药依从性问卷评分及世界卫生组织生存质量测定量表简表各维度评分比较差异均有统计学意义(P<0.05),蒙特利尔认知评估量表评分与汉密顿抑郁量表及贝克-拉范森躁狂量表评分呈显著负相关(P<0.05),与Morisky用药依从性问卷评分、世界卫生组织生存质量测定量表简表的心理领域、生理领域、环境领域和社会领域评分均呈显著正相关(P<0.05)。结论双相情感障碍患者认知功能水平越高,抑郁和躁狂症状越轻,服药依从性和生活质量越高,临床上可以通过认知干预提高患者的认知功能,改善预后。
Objective To explore the correlation between cognitive function and depression,mania,medication compliance and quality of life in patients with bipolar disorder.Methods The cognitive function of 118 patients with bipolar disorder was assessed by Montreal cognitive assessment(MoCA).The scores of Hamilton depression scale(HAMD),Bech-Rafaelsdn mania rating scale(BRMS),Morisky medication adherence scale-8(MMAS-8) and the World Health Organization quality of life-BREF(WHOQOL-BREF)in patients with different levels of cognitive function were compared,and the correlation between cognitive function and depression,mania,medication compliance and quality of life was analyzed.Results There were significant differences in the scores of HAMD,BRMS,MMAS-8 and WHOQOL-BREF among patients with different cognitive function levels(P < 0.05).MoCA score was negatively correlated with HAMD and BRMS scores(P<0.05),and positively correlated with MMAS-8,psychological field,physiological field,environmental field and social field of WHOQOL-BREF(P<0.05).Conclusions The higher the level of cognitive function in patients with bipolar disorder,the lower the symptoms of depression and mania,the higher the medication compliance and the quality of life.Cognitive intervention can be clinically used to improve the cognitive function of patients and improve the prognosis.
作者
张富松
陈延会
Zhang Fusong;Chen Yanhui(The Fifth People's Hospital of Kaifeng City,Kaifeng 475003,Henan,China)
出处
《临床心身疾病杂志》
CAS
2022年第1期133-135,共3页
Journal of Clinical Psychosomatic Diseases
关键词
双相情感障碍
认知功能
抑郁
躁狂
服药依从性
生活质量
bipolar disorder
cognitive function
depression
mania
medication compliance
quality of life
