摘要
目的评价WHOQOL HIV-BREF量表用于评价经高效抗反转录病毒治疗(HARRT)的艾滋病(AIDS)病人的信度、效度。方法 2008年7月-2009年6月,使用AIDS病人生存质量调查表,对102例确诊的AIDS病人进行调查,内容包括HIV-BREF量表、基本人口学资料以及AIDS相关症状等;采用相关分析、信度分析、因子分析和方差分析等统计方法考察量表的信度、效度和区分度。结果 HIV-BREF量表每个领域的分半信度和内部一致性信度系数>0.60,重测信度系数>0.50。每个条目跟相关领域的相关系数都>0.54(有统计学意义),大于该条目与其他领域的相关系数。因子分析提取的6个主成分分别代表了各个领域,累计贡献达到72.46%;其结果与量表的理论结构假设基本一致。HIV-BREF量表能够区分是否吸毒、不同感染阶段病人的生存质量,具有较好的区分度。结论 HIV-BREF量表有较好的信度、效度和区分度,在临床以及科研中,可用于评价AIDS病人的生存质量。
Objective To evaluate the reliability and validity of WHOQOL HIV-BREF scale used for AIDS patients who received highly active antiretroviral therapy （HARRT）. Methods From July 2008 to June 2009,102 AIDS patients were face-to-face interviewed with the WHOQOL HIV-BREF scale,demographic questionnaire and AIDS related symptom checklist. And then correlation analysis,reliability analysis,factor analysis,t-test analysis and analysis of variance were used to evaluate the validity,reliability and discrimination of the scale. Results The split-half reliability and internal consistency reliability coefficient of each domain of HIV-BREF was 0.60. The test-retest reliability coefficient was 0.50. The correlation coefficient between each item and its domain was 0.54 （statistically significant）,which was greater than the correlation between the item and other domains. Six principal components extracted from the items were representative of all domains of the scale and the cumulative variance was 72.46%. The result of the factor analysis revealed that the constructs of the scale obtained were consistent with the conceived concept in essence. HIV-BREF scale had good discrimination,for it showed significantly different QOL in different drug status and infectious stages. Conclusions HIV-BREF scale has good reliability,validity and discrimination,and it can be used for the evaluation of quality of life among AIDS patients in clinical practice and scientific research.
出处
《中国艾滋病性病》
CAS
2010年第3期239-242,共4页
Chinese Journal of Aids & STD
基金
艾滋病和病毒性肝炎等重大传染病防治科技重大专项(编号:2008ZX10005-012)~~
