摘要
目的:探讨在全麻子宫切除术中应用右美托咪啶对术中血流动力学及应激反应的影响。方法:以平煤神马医疗集团总医院2018年9月1日至2019年9月1日收治的305例腹腔镜全麻子宫切除术患者进行分析,以随机数字法将患者分成对照组(152例)以及观察组(153例)。对照组采用0.9 %氯化钠注射液,观察组采用右美托咪啶,观察分析两组患者具体情况。结果:两组患者麻醉诱导前的血流动力学指标比较,差异均无统计学意义(P>0.05);观察组患者术毕即刻的心率(HR)、平均动脉压(MAP)以及收缩压(SBP)均低于对照组,差异具有统计学意义(P<0.05);观察组患者皮质醇(Cor)、白细胞介素–6(IL–6)以及去甲肾上腺素(NE)水平均低于对照组,差异具有统计学意义(P<0.05)。结论:在全麻子宫切除术中应用右美托咪啶实施麻醉,可有效改善患者血流动力学指标,同时还可减轻应激反应。
Objective To investigate and analyze the effects of dexmedetomidine on intraoperative hemodynamics and stress response during hysterectomy under general anesthesia.Methods A total of 305 patients with hysterectomy under general anesthesia admitted to Pingmei Shenma Medical Group General Hospital from September 1,2018 to September 1,2019 were analyzed.All patients were divided into control group with 152 cases and observation group with 153 cases by random number method.The control group was given 0.9% sodium chloride injection,the observation group was given dexmedetomidine,and the specific situation of the two group were observed and analyzed.Results There was no statistical significance in hemodynamic indexes before anesthesia induction between two groups (P > 0.05).The heart rate (HR),mean arterial pressure (MAP) and systolic blood pressure (SBP) of the observation group immediately after operation were lower than those of the control group,the differences were statistically significant (P < 0.05).The levels of cortisol (Cor),interleukin-6 (IL-6) and norepinephrine (NE) in the observation group were lower than those of the control group,and the differences were statistically significant (P < 0.05).Conclusion Dexmedetomidine can effectively improve the hemodynamics indexes of patients and reduce stress response during hysterectomy under general anesthesia.
作者
薛源
张立群
XUE Yuan;ZHANG Li-qun(General Hospital of Pingmei Shenma Group,Henan Pingdingshan 467000)
出处
《深圳中西医结合杂志》
2021年第22期58-60,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
