摘要
目的分析甲状腺手术患者全身麻醉时应用不同剂量右美托咪定对患者苏醒时间及拔管期心血管系统的影响。方法于重庆市开州区南山路开州区人民医院2017年1月—2019年1月期间收治的甲状腺手术患者中选取86例,分为两组,均给予右美托咪定静脉滴注,低剂量组使用剂量为0.5μg/kg,高剂量组为1.0μg/kg,比较两组患者的苏醒期间和不同时间点血压和心率变化情况。结果低剂量组在T1、T2、T3时的SBP、DBP和HR均高于高剂量组(P<0.05)。低剂量组麻醉苏醒时间为(15.4±2.8)min,拔管时间为(18.9±2.5)min,显著短于高剂量组(P<0.05)。低、高剂量组定向力恢复时间为(24.3±5.2)min和(30.8±6.4)min,组间差异有统计学意义(P<0.05)。结论应用0.5μg/kg右美托咪定更有助于减轻甲状腺手术患者的应激反应,保持拔管期心血管系统稳定,缩短患者苏醒时间和定向力恢复时间,提高患者生活质量。
Objective To analyze the effects of dexmedetomidine at different doses on recovery time and cardiovascular system during extubation in patients undergoing thyroidectomy under general anesthesia.Methods 86 patients with thyroid surgery admitted to Kaizhou District People’s Hospital of Nanshan Road from January 2017 to January 2019 were divided into two groups.They were given dexmedetomidine intravenously.The dosage of dexmedetomidine was 0.5 ug/kg in the low-dose group and 1.0 ug/kg in the high-dose group.The changes of blood pressure and heart rate during awakening and at different time points were compared between the two groups.Results SBP,DBP and HR at T1,T2 and T3 in low dose group were higher than those in high dose group(P<0.05).The recovery time of anesthesia in the low dose group was(15.4±2.8)min,and the extubation time was(18.9±2.5)min,which was significantly shorter than that in the high dose group(P<0.05).The recovery time of orientation in low and high dose groups was(24.3±5.2)min and(30.8±6.4)min,with significant difference between the two groups(P<0.05).Conclusion The application of 0.5 ug/kg dexmedetomidine is more helpful to alleviate the stress response of patients undergoing thyroid surgery,maintain the stability of cardiovascular system during extubation,shorten the recovery time of awakening and orientation,and improve the quality of life of patients.
作者
任大鹏
张春燕
蒋亚明
苟子瀚
REN Dapeng;ZHANG Chunyan;JIANG Yaming;GOU Zihan(Department of Anesthesiology,Kaizhou District People's Hospital of Nanshan Road,Chongqing 405400,China)
出处
《中国全科医学》
CAS
北大核心
2020年第S01期113-115,共3页
Chinese General Practice
关键词
苏醒时间
不同剂量
甲状腺手术
右美托咪定
心血管系统
Awakening time
Different doses
Thyroid surgery
Dexmedetomidine
Cardiovascular system
