摘要
目的提高医院合理用药水平。方法收集医院信息系统2019年1月至12月的住院医嘱,统计并比较处方前置审核实施前(2019年1月至6月)、实施后(2019年7月至12月)的医嘱不合理率、不合理类型及临床退药率。结果实施后的医嘱不合理率和退药率分别为1.25%(2 576/206 808)和2.20%(38 478/1 748 880),均低于实施前的2.02%(4 704/233 014)和3.20%(48 306/1 510 756),差异有统计学意义(P <0.01);不合理处方类型中,用药不适宜处方主要表现为适应证不适宜、用法用量不适宜,不规范处方主要表现为医师签名、签章不规范或与签名、签章的留样不一致,超常处方主要表现为无正当理由超说明书用药。结论开展处方前置审核可降低医嘱不合理率和退药率,促进临床合理用药。
Objective To improve the level of rational drug use in the hospital.Methods The inpatient orders in the hospital information system(HIS) from January to December 2019 were collected,and the unreasonable rate,unreasonable types and clinical withdrawal rate of orders before(from January to June 2019) and after(from July to December 2019) the implementation of prescription pre-audit were compared.Results After the implementation of prescription pre-audit,the unreasonable rate and drug withdrawal rate of the orders were 1.25%(2 576/206 808) and 2.02%(38 478/1 748 880),which were significantly lower than2.02%(4 704/233 014) and 3.20%(48 306/1 510 756) before implementation(P <0.01).Among the unreasonable types of prescriptions,the inappropriate prescriptions were mainly manifested in inappropriate indications,inappropriate usage and dosage,the non-standard prescriptions were mainly manifested in the non-standard signature and seal of doctors or inconsistent with the sample of signature and seal,and unconventional prescriptions were mainly manifested in the off-lable drug use without justified reasons.Conclusion The implementation of prescription pre-audit can reduce the unreasonable rate and drug withdrawal rate of orders,and promote clinical rational drug use.
作者
张雅鑫
冀召帅
张维
郭新媛
毛乾泰
艾超
ZHANG Yaxin;JI Zhaoshuai;ZHANG Wei;GUO Xinyuan;MAO Qiantai;AI Chao(Beijing Tsinghua Changgung Hospital·School of Clinical Medicine,Tsinghua University,Beijing,China 102218)
出处
《中国药业》
CAS
2022年第3期12-14,共3页
China Pharmaceuticals
基金
北京清华长庚医院青年基金项目[12017C1001]。
关键词
处方前置审核
合理用药
住院医嘱
药房管理
prescription pre-audit
rational drug use
inpatient orders
pharmacy management
