摘要
目的分析单纯乳头状甲状腺癌(PTC)与PTC合并桥本甲状腺炎(HT)患者的临床特点。方法将149例PTC患者,按是否合并HT分为PTC组(n=120)与HT-PTC组(n=29)。对比两组患者的性别、年龄、术前促甲状腺激素(TSH)水平、甲状腺微小乳头状癌(PTMC)发生率、术后左旋甲状腺激素剂量以及术后TSH抑制治疗达标情况等临床特征。结果两组患者年龄、PTMC发生率、术前TSH水平、左旋甲状腺激素剂量比较,差异均无统计学意义(P﹥0.05);HT-PTC组女性比例高于PTC组,TSH抑制治疗达标率高于PTC组,差异均有统计学意义(P﹤0.05)。结论HT合并PTC更好发于女性,术后TSH抑制治疗时较单纯PTC达标率高。
Objective To analyze the clinical characteristics of simple papillary thyroid carcinoma(PTC)and PTC complicated with Hashimoto thyroiditis(HT).Method A total of 149 PTC patients were divided into PTC group(n=120)and HT-PTC group(n=29);the clinical characteristics of the two groups were compared,including gender,age,preoperative thyroid-stimulating hormone(TSH)level,incidence of papillary thyroid microcarcinoma(PTMC),postoperative levothyroxine dose,and compliance rate of postoperative TSH inhibition therapy.Result There were no significant differences in age,incidence of PTMC,preoperative TSH level and levothyroxine dose between two groups(P>0.05);there were more female patients in HT-PTC group than PTC group,and compliance rate of postoperative TSH inhibition therapy in HT-PTC group was higher than that in PTC group(P<0.05).Conclusion HT complicated with PTC is more common in women,and TSH inhibition therapy has a higher compliance rate than PTC alone.
作者
祖瓦丽亚古丽·艾合买提
张洁
Zuwaliyaguli·Aihemaiti;ZHANG Jie(Department of Endocrinology,People’s Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,Xinjiang,China)
出处
《癌症进展》
2021年第23期2402-2404,共3页
Oncology Progress
基金
新疆维吾尔自治区自然科学基金(2018D01C126)。
关键词
乳头状甲状腺癌
桥本甲状腺炎
临床特征
papillary thyroid carcinoma
Hashimoto thyroiditis
clinical characteristic
