摘要
目的观察中药方剂疏肝散结散联合左旋甲状腺激素对气滞痰凝型良性甲状腺结节的治疗效果。方法本研究选取天津中医药大学第一附属医院2017年8月—2020年8月收治的气滞痰凝型良性甲状腺结节患者300例为观察对象,依照随机数字表法分为对照组和观察组各150例。对照组给予左甲状腺素钠片口服治疗,观察组在对照组治疗的基础上联合应用疏肝散结散进行中药干预。连续治疗30 d后,比较两组临床疗效、甲状腺生化指标、甲状腺结节影像学检查和中医症候积分。结果观察组治疗后总有效率为78.67%,高于对照组的61.33%;观察组甲状腺结节最长径、结节体积低于对照组;观察组中医症候积分低于对照组,差异均有统计学意义(P<0.05)。结论在气滞痰凝型甲状腺结节的临床治疗中,应用中药方剂疏肝散结散联合左旋甲状腺激素,能有效缓解临床症状,值得临床推广应用。
Objective To observe the therapeutic effect of Shugan Sanjie Decoction combined with levothyroxine on benign thyroid nodules of qi stagnation and phlegm coagulation type.Methods In this study,300 patients with benign thyroid nodules of qi stagnation and phlegm coagulation type admitted to the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from August 2017 to August 2020 were selected as the observation objects.According to the random number table method,they were divided into the control group and the observation group,with 150 cases in each group.The control group was given sodium levothyroxine oral treatment,while the observation group was given Shugan Sanjie Decoction on the basis of the control group.After 30 days of continuous treatment,the clinical efficacy,thyroid biochemical indexes,thyroid nodule imaging examination and TCM syndrome score of the two groups were compared.Results The total effective rate of the observation group was 78.67%,higher than 61.33% of the control group;the longest diameter and volume of thyroid nodules in the observation group were lower than those in the control group;the TCM symptom score of the observation group was lower than that of the control group,and the differences above all were statistically significant(P<0.05).Conclusion In the clinical treatment of qi stagnation and phlegm coagulation type of thyroid nodules,the application of Shugan Sanjie decoction combined with levothyroxine could effectively relieve clinical symptoms and improve the therapeutic effect,which was worthy of clinical promotion and application.
作者
邵荣江
宋晓冬
卢宏亮
路军华
葛善义
孙勃
SHAO Rong-jiang;SONG Xiao-dong;LU Hong-liang;LU Jun-hua;GE Shan-yi;SUN Bo(General Surgery Department,the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China)
出处
《中国城乡企业卫生》
2021年第6期4-7,共4页
Chinese Journal of Urban and Rural Enterprise Hygiene
关键词
良性甲状腺结节
气滞痰凝型
疏肝散结散
左旋甲状腺激素
中西医结合
Benign thyroid nodules
Qi stagnation and phlegm coagulation type
Shugan Sanjie Decoction
Levothyroxine
Integrated traditional Chinese and Western Medicine
