摘要
目的分析甲状腺乳头状癌合并桥本甲状腺炎患者的临床病理特征。方法选取2017年3月至2121年3月本院收治的50例甲状腺癌患者作为研究对象,根据术后病理诊断结果不同分为A组(单纯甲状腺乳头状癌,n=29)和B组(甲状腺乳头状癌合并桥本甲状腺炎,n=21)。观察比较两组临床病例表现,收集两组患者一般信息、临床资料、术前检查资料、术后病理检查资料,将收集到的数据输入电脑,采用回顾性方法对资料进行分析,总结甲状腺乳头状癌合并桥本甲状腺炎的病理特征。结果A组肿瘤直径为(1.37±0.26)cm,大于B组的(0.98±0.21)cm(P<0.001);A组包膜有侵犯率为34.48%、中央区淋巴结转移率为62.07%、甲状腺肿大率为75.86%、颈部压迫率为65.52%,均高于B组的9.52%、33.33%、23.81%、33.33%(P<0.001或<0.05);A组双侧甲状腺癌率为20.69%、多发肿瘤病灶率为31.03%、颈侧区淋巴结转移率为20.69%、TNM分期Ⅰ期比例为72.41%、TNM分期Ⅱ期比例为24.14%、TNM分期Ⅲ期比例为0.00%、TNM分期Ⅳ期比例为3.45%,与B组的19.05%、33.33%、19.05%、71.43%、23.81%、3.23%、0.00%比较差异无统计学意义;A组血促甲状腺激素(2.69±0.56)IU/ml,低于B组的(3.28±0.82)IU/ml(P<0.05)。结论甲状腺乳头状癌合并桥本甲状腺炎疾病具有明显的临床病理特征,可作为区分单纯甲状腺乳头状癌的依据,以为患者提供确切治疗方案,提升预后效果。
Objective To analyze the clinicopathological characteristics of papillary thyroid carcinoma with Hashimoto's thyroiditis.Methods 50 patients with thyroid cancer admitted to our hospital from March 2017 to March 2121 were selected as research subjects,and they were divided into group A(simple papillary thyroid cancer,n=29)and group B(papillary thyroid cancer complicated with Hashimoto's thyroiditis,n=21)according to different postoperative pathological diagnosis results.The differences of clinical manifestations between the two groups were observed,general information,clinical data,preoperative examination data,and postoperative pathological examination data of the two groups were collected,and the collected data were entered into a computer and analyzed retrospectively,the pathological characteristics of papillary thyroid carcinoma combined with Hashimoto's thyroiditis were summarized.Results The tumor diameter of group A(1.37±0.26)cm was larger than that of group B(0.98±0.21)cm(P<0.001);The percentages of patients with capsular invasion(34.48%),central regional lymph node metastasis(62.07%),goiter(75.86%),and neck compression(65.52%)in group A were higher than those in group B(9.52%,33.33%,23.81%,33.33%)(P<0.001 or<0.05);In group A,the rate of bilateral thyroid cancer was 20.69%,multiple tumor lesions was 31.03%,lymph node metastasis in the lateral cervical region was 20.69%,TNM stageⅠwas 72.41%,TNM stageⅡwas 24.14%,TNM stageⅢwas 0.00%,TNM stageⅣwas 3.45%,there was no significant differences compared with 19.05%,33.33%,19.05%,71.43%,23.81%,3.23%,0.00%in group B;Blood thyroid stimulating hormone in group A(2.69±0.56)IU/ml was lower than that in group B(3.28±0.82)IU/ml(P<0.05).Conclusion Papillary thyroid carcinoma combined with Hashimoto's thyroiditis has obvious clinicopathological characteristics,which can be used as the basis to distinguish simple papillary thyroid carcinoma from the disease,provide patients with more appropriate treatment for their disease,and improve their prognosis.
作者
黄小杏
梁秀冰
曾庆苏
HUANG Xiaoxing;LIANG Xiubing;ZENG Qingsu(Department of Pathology,People's Hospital of Yangjiang City,Guangdong Province,Yangjiang,Guangdong,529500,China)
出处
《当代医学》
2022年第29期159-161,共3页
Contemporary Medicine
关键词
甲状腺乳头状癌
桥本甲状腺炎
病理特征
Papillary thyroid carcinoma
Hashimoto thyroiditis
Pathological features
