摘要
目的分析病理确诊的608例原发性甲状腺癌的临床病理特征。方法采用回顾性分析的方法对天津医科大学附属肿瘤医院2007年6月至2010年12月病理确诊的608例甲状腺癌患者进行临床病理资料分析。结果608例甲状腺癌患者中,男219例,女389例,乳头状癌(451例)占74.2%,无具体分类腺癌(114例)占18.8%,滤泡性甲状腺癌(22例)占3.6%,髓样癌(13例)占2.1%,未分化癌(8例)占1.3%,淋巴结转移阳性率分别为56.3%、46.5%、45.5%、69.2%、37.5%;髓样癌最易合并局域淋巴结转移。其中219例(36.0%)侵出包膜,207例(34.0%)侵出腺叶,83例(13.7%)侵犯周围组织器官。32例(5.3%)合并桥本氏甲状腺炎,107例(17.6%)合并结节性甲状腺肿,14例(2.3%)合并腺瘤性甲状腺肿。其中肿瘤侵出包膜、侵出腺叶、侵犯周围组织器官的淋巴结转移率差异有统计学意义,其淋巴结转移率分别为66.2%、66.2%、81.6%。淋巴结分区中,最易转移的部位为分别为Ⅵ区(38.80%)、Ⅳ区(20.23%)、Ⅲ区(20.02%)、Ⅱ区(12.33%)、Ⅴ区(4.91%)、Ⅶ区(3.54%)、Ⅰ(0.37%)。结论甲状腺癌最常见的为乳头状癌,其次为腺癌(无具体分类),滤泡性甲状腺癌居第3位;髓样癌最易合并局域淋巴结转移。侵出包膜、侵出腺叶、侵犯周围组织器官的淋巴结转移率差异有统计学意义;淋巴结分区中,最易转移的部位为分别为Ⅵ、Ⅳ、Ⅲ、Ⅱ、Ⅴ、Ⅶ、Ⅰ区。
Objective To analyze the clinical and pathological features of 608 cases with pathologically confirmed primary thyroid carcinoma.Methods Analysis of clinical and pathological data of 608 cases of thyroid cancer patients in Tumor Hospital Affiliated to Tianjin Medical University from June 2007 to December 2010.Results 608 cases of thyroid cancer patients,male 219 cases,female 389 cases,papillary carcinoma(451 cases)accounted for 74.2%,no specific classification adenocarcinoma accounted for 18.8%(114 cases),follicular thyroid carcinoma in third(22 cases)accounted for 3.6%,medullary carcinoma(13 cases)accounted for 2.1%,anplastic carcinoma(8 cases)accounted for 1.3%,their positive lymph node metastasis rate were 56.3%,46.5%,45.5%,69.2%,37.5%respectively.Medullary carcinoma most easily combined with local lymph node metastasis.Among the 219 cases(36.0%)invading capsule,207 cases(34.0%)invading glandular lobe,83 cases(13.7%)invading surrounding tissue and organ.In 32 cases(5.3%)with Hashimoto’s thyroiditis,107 cases(17.6%)complicated with nodular goiter,14 cases(2.3%)with adenomatous goiter.The invasion of capsulegland,invasion,invasion of surrounding tissues and organs of the lymph nodemetastasis rate difference has statistics significance,the lymph node metastasis rate were 66.2%,66.2%,81.6%.Lymph node partition,the easy transfer of parts were VI(38.80%),IV(20.23%),III(20.02%),II(12.33%),V(4.91%),VII(3.54%),I(0.37%).Conclusion The most common thyroid cancer for papillary carcinoma,secondly adeno carcinoma(no specific classification),follicular thyroid carcinoma ranks third;medullary carcinoma most easily combined with local lymph node metastasis.Invasion of capsule,invading gland,invasion of surrounding tissues and organs of the lymph node metastasis rate difference was statistically significant;lymph node partition,the easy transfer of parts were VI,IV,III,II,V,VII,I.
作者
李小刚
黄治虎
魏松峰
张艳
Li Xiaogang;Huang Zhihu;Wei Songfeng;Zhang Yan(Department of General Surgery,The First Affiliated Hospital of Baotou Medical College,Baotou,Inner Mongolia,014010,China;Department of Tumor Chemotherapy,AnhuiWanbei Coal Group General Hospital,Anhui,Suzhou,234011,China;Head and Neck Surgery,Tumour Hospital Affiliated to Tianjin Medical University,Tianjin,300060,China)
出处
《当代医学》
2020年第1期67-69,共3页
Contemporary Medicine
基金
内蒙古自治区自然科学基金项目（2017MS0859)
关键词
甲状腺癌
临床病理
淋巴结转移
Thyroid carcinoma
Clinical Pathology
Lymphatic metastasis
