摘要
目的描述流感病毒感染对发热门诊初诊的流感样病例经济负担和临床结局影响,加强公众对流感的认知和重视程度,提高防病治病意识。方法采用前瞻性研究,针对发热门诊初诊的流感样病例,以流感病毒核酸检测阳性、阴性分为流感组和非流感组,收集临床资料,随访患者预后情况。结果最终纳入520例流感样病例,包括流感组271例和非流感组249例。流感组人均总门诊费用为(632.51±262.21)元,非流感组人均总门诊费用为(626.51±387.31)元,差异无统计学意义。与非流感组比较,流感组流感快速检测和抗病毒药物比例高,复诊次数少、静脉输液、静脉采血、抗菌药物处方、对症药物处方例数、抗菌药物费用、医事服务费、治疗费均更低(P<0.05)。在病情转归方面,流感组和非流感组患者就诊后发热持续时间为2.4天、症状持续时间为2.9天,差异无统计学意义,但流感组患者遗留咳嗽比例更高(P<0.05)。流感组患者请病假时间更长(P<0.05),引起家人发病,高于非流感组(17.5%vs.6.2%,P<0.05)。结论流感病毒感染对发热门诊流感样病例的直接经济负担无影响,但流感组复诊次数和抗菌药物处方较少,病假时间更长,引起周围人发病比例更高,应加强对流感防控。
OBJECTIVE To describe the impact of influenza virus infection on the economic burden and clinical outcome of newly diagnosed influenza-like cases with fever in the outpatient department,and to strengthen the public’s awareness and attention to influenza and improve the awareness of disease prevention and treatment.METHODS In this prospective study,newly diagnosed influenza-like cases with fever were divided into the influenza group and non-influenza group according to the positive and negative nucleic acid tests of influenza virus in the outpatient department.Clinical data were collected,and the prognosis of the patients was followed up.RESULTS Total of 520 patients with influenza-like illness were included,including 271 in the influenza virus group and 249 in the non-influenza virus group.The total outpatient cost per capita was(632.51±262.21)yuan in the influenza virus group and was(626.51±387.31)yuan in the non-influenza virus group.Compared with the non-influenza group,the influenza group had a higher proportion of rapid detection of influenza and use of antiviral drugs,and the numbers of follow-up visits,intravenous infusion,venous blood sampling,antibiotic prescription,symptomatic drug prescription,antibiotic cost,medical service cost and treatment cost were significantly lower(P<0.05).In terms of disease outcome,the fever duration was 2.4 days and the symptom duration was 2.9 days in the influenza group and non-influenza group,respectivel;the difference was not significant.But the proportion of residual cough and in the influenza group was significantly higher(P<0.05).Patients in the influenza virus group took longer sick leave(P<0.05),17.5%of whose family members became ill,compared with that of 6.2%in the non-influenza virus group(P<0.05).CONCLUSION Influenza virus infection had no effect on the direct economic burden of influenza-like illness in fever clinics.But the number of return visits and antibiotic prescriptions were lower in influenza virus group,with longer sick leave duration and higher in
作者
李晓光
林菲
陈静
王伟
胥婕
卢庆彬
LI Xiao-guang;LIN Fei;CHEN Jing;WANG Wei;XU Jie;LU Qing-bin(Peking University Third Hospital,Beijing100191,China;不详)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2021年第8期1272-1276,共5页
Chinese Journal of Nosocomiology
基金
科技部重大专项基金资助项目(2017ZX10103004,2018ZX10732401-003)
北京市海淀区预防医学会基金资助项目(2017HDPMA04)。
