摘要
目的观察卡舒宁联合流感疫苗对老年性慢性支气管炎合并急性感染的防治效果。方法选择多年反复感染、咳嗽、咳痰、不同程度哮喘的老年慢性支气管炎患者138人,随机分为观察组73人,对照组65人。观察组接种流感疫苗后2周注射卡舒宁,每周2次,疗程3个月;对照组仅注射卡舒宁,方法同观察组。1年后,对两组病例统一进行电话或入户随访,内容包括慢性支气管炎急性感染次数、急性感染时住院次数及急性感染时抗生素治疗疗程。结果观察组患者慢性支气管炎急性感染次数和住院总次数明显减少,抗生素治疗疗程明显缩短,与对照组相比,差异均有统计学意义(P<0.01)。结论卡舒宁联合流感疫苗可明显提高老年性慢性支气管炎合并急性感染的防治效果。
Objective To observe the preventive and curative effects of Card Shu Ning combined with influenza vaccine on senile chronic bronchitis complicated with acute infection.Methods A total of 138 patients with senile chronic bronchitis complicated with cough,expectoration and asthma at various degrees,who were infected repeatedly during the past years,were divided into trial（73 cases） and control（65 cases） groups randomly.The patients in trial group were inoculated with influenza vaccine and injected with Card Shu Ning 2 weeks later,while those in control group were injected with Card Shu Ning alone,twice a week for 3 months.Telephone or in-home follow-up was performed on the patients one year later,including the times of acute infection with chronic bronchitis,times of hospitalization due to acute infection and the course of treatment of acute infection with antibiotics.Results Compared with those in control group,the times of acute infection with chronic bronchitis and the times of hospitalization due to acute infection of patients in trial group decreased significantly,while the course of treatment with antibiotics was shortened significantly（P 0.01）.Conclusion Card Shu Ning combined with influenza vaccine improved the preventive and curative effect of senile chronic bronchitis significantly.
出处
《中国生物制品学杂志》
CAS
CSCD
2011年第10期1214-1216,共3页
Chinese Journal of Biologicals
关键词
卡舒宁
流感疫苗
老年人
支气管炎
慢性
急性感染
Card Shu Ning
Influenza vaccine
Senile
Bronchitis
chronic
Acute infection
