摘要
银屑病是一种免疫介导的系统性心身疾病,不仅伴发心血管疾病、代谢性疾病及自身免疫相关疾病的风险升高,抑郁、焦虑、痴呆及睡眠障碍等精神心理障碍疾病在银屑病逐渐引起重视。精神、心理因素可以通过神经-内分泌-免疫网络对银屑病的发生和发展起作用,本文对银屑病人群中心理、精神疾病共病进行概述,系统分析心理、精神障碍在银屑病的风险及发病机制,加深对银屑病和心理、精神相关共病的认识。
Psoriasis is an immune-mediated systemic psychosomatic disease,with an increased risk of cardiovascular disease,metabolic disease and autoimmune related diseases.Besides,mental and psychological disorders such as depression,anxiety,dementia and sleep disorders attracted attention of society.Mental and psychological factors can play a role in the occurrence and development of psoriasis through neuroendocrine-immune network.This paper describes the comorbidity of psychological and mental disorders in psoriasis population,systematically analyzes the risk and pathogenesis of psychological and mental disorders in psoriasis,and deepens the cognition of psoriasis and psychological and mental comorbidity.
作者
史玉玲
SHIYuling(Shanghai Skin Disease Hospital,Tongji University School of Medicine,Shanghai 200000,China)
出处
《皮肤科学通报》
2021年第2期108-112,M0003,共6页
Dermatology Bulletin
基金
国家自然科学基金(No.81872522,82073429)
上海市教委“科研创新计划”自然科学重大项目(No.2019-01-07-00-07-E00046)
上海市优秀学术带头人计划(No.20XD1403300)
上海市卫健委优秀学科带头人计划(No.2018BR30)
上海申康医院发展中心临床三年行动计划(No.SHDC2020CR1014B,SHDC12018X06)。
关键词
银屑病
抑郁
焦虑
心理、精神障碍
Psoriasis
Depression
Anxiety
Mental and psychiatric disorders
