摘要
目的:研究翼状胬肉切除联合颞上方角膜缘干细胞移植术治疗翼状胬肉患者的疗效。方法:研究对象为2019年1月至2020年1月入院的60例翼状胬肉患者,按照简单随机分组法随机分为两个小组(研究组与对照组各30例);对照组单用翼状胬肉切除术治疗,研究组联用翼状胬肉切除术与颞上方角膜缘干细胞移植术治疗;比较两组手术前后角膜散光度、裸眼视力与术后角膜创面愈合时间、总有效率、并发症发生率及复发率。结果:两组术前角膜散光度、裸眼视力无差异(P>0.05);两组术后较术前角膜散光度更低,裸眼视力更高(P<0.05);研究组较对照组术后角膜散光度、复发率更低,裸眼视力、总有效率更高,角膜创面愈合时间更短(P<0.05)。两组并发症无差异(P>0.05)。结论:翼状胬肉切除联合颞上方角膜缘干细胞移植术治疗翼状胬肉患者的效果显著,可有效降低患者角膜散光度,改善其裸眼视力水平,并可促使角膜创面快速愈合,且并发症发生率及复发率均较低。
Objective:To study the efficacy of pterygium excision combined with superior temporal limbal stem cell transplantation in the treatment of pterygium.Methods:A total of 60 pterygium patients admitted to hospital from January 2019 to January 2020 were divided into two groups according to the random number table method,one group was the control group,According to the simple random grouping method,they were randomly divided into two groups(study group and control group with 30 cases each).The control group was treated with pterygium excision alone,while the study group was treated with pterygium excision combined with superior temporal limbal stem cell transplantation.Before and after operation,corneal astigmata,naked eye vision,postoperative corneal wound healing time,total effective rate,complication rate and recurrence rate were compared between the two groups.Results:there was no difference in preoperative corneal astigmatism and naked eye vision between the two groups(P>0.05).The postoperative corneal astigmatism of the two groups was lower than that of the preoperative,and the visual acuity of the naked eye was higher(P<0.05).Compared with the control group,the study group had lower postoperative keratodispersion and recurrence rates,higher naked eye vision and total effective rate,and shorter corneal wound healing time(P<0.05).There was no difference in postoperative complication rate between the two groups(P>0.05).Conclusion:Pterygium excision combined with superior temporal limbal corneal dry cell transplantation is effective in the treatment of pterygium patients,which can effectively reduce the patients'corneal astigmata,improve the level of naked eye vision,and promote the rapid healing of corneal wound,with low complication rate and recurrence rate.
作者
杨俊臣
程婷玉
程意农
吴文芳
YANG Junchen;CHENG Tingyu;CHENG Yinong(The People's Hospital of Huangshan City,Anhui Huangshan 245000,China)
出处
《河北医学》
CAS
2021年第2期301-305,共5页
Hebei Medicine
基金
安徽省卫生厅科研课题,(编号:17HA01286)。
关键词
翼状胬肉
翼状胬肉切除术
颞上方角膜缘干细胞移植术
角膜散光
裸眼视力
Pterygium
Pterygium excision
Transplantation of superior temporal limbal stem cells
Corneal astigmatism
The naked eye eyesight
