摘要
目的研究替格瑞洛片治疗冠心病的疗效与患者的不良反应率情况。方法于本院选取74例冠心病患者,对照组患者给予氯吡格雷片治疗,观察组患者给予替格瑞洛片治疗,从治疗有效率、用药后不良反应率、身体变化指标等方面展开分析。结果用药后观察组患者血小板聚集率、血浆浓度、左室收缩/舒张末期内径分别为(50.21±4.29)%、(1.52±0.23)mPa·s、(35.44±3.13)/(54.27±2.52)mm明显低于对照组的(62.43±3.62)%、(2.38±0.61)mPa·s、(40.25±3.11)/(59.72±3.23)mm,左室射血分数(57.82±2.41)%明显高于对照组(51.31±2.93)%,差异明显(P<0.05)。两组不良反应率方面无统计学意义(P>0.05)。结论替格瑞洛片治疗冠心病具有较为显著的疗效,可有效控制出血风险的发生,促使患者快速恢复心功能与凝血功能。
Objective To study the efficacy of ticagrelor tablets in the treatment of coronary heart disease and the adverse reaction rate of patients.Methods In our hospital,74 patients with coronary heart disease were selected.The control group was treated with clopidogrel tablets,and the observation group was treated with ticagrelor tablets.The treatment efficiency,adverse reaction rate after medication,and physical changes index analyze aspects.Results The platelet aggregation rate,plasma concentration,left ventricular systolic/end diastolic diameter(50.21±4.29)%,(1.52±0.23)mPa·s,(35.44±3.13)/(54.27±2.52)mm in the observation group were significantly lower than those in the control group(62.43±3.62)%,(2.38±0.61)mPa·s,(40.25±3.11)/(59.72±3.23)mm,the left ventricular ejection fraction(57.82±2.41)%was significantly higher than that in the control group(51.31±2.93)%(P<0.05).The adverse reaction rate of the two groups was not statistically significant(P>0.05).Conclusion Ticagrelor tablets have a significant curative effect in the treatment of coronary heart disease,which can effectively control the risk of bleeding and prompt patients to quickly restore heart and coagulation functions.
作者
吴宝村
WU Baocun(Haicheng Central Hospital,Haicheng 114200,China)
出处
《中国医药指南》
2021年第1期90-91,共2页
Guide of China Medicine
关键词
冠心病
替格瑞洛片
氯吡格雷片
不良反应
Coronary heart disease
Ticagrelor tablets
Clopidogrel tablets
Adverse reactions
