摘要
目的分析口腔黏膜病患者外周血淋巴细胞亚群的特征。方法选取90例口腔黏膜病患者和50例健康体检者作为研究对象,分为观察A组(复发性阿弗他溃疡)49例、观察B组(口腔扁平苔藓)41例和对照组(健康体检者)50例,检测外周血淋巴细胞亚群。结果与对照组相比,观察A组患者的CD3^+、CD3^+CD8^+显著更高(P<0.05),CD3^+CD4^+、CD4^+/CD8^+、CD3-CD19^+显著更低(P<0.05);观察B组患者的CD3^+CD8^+显著更低(P<0.05)。与观察B组患者相比,观察A组患者的CD3^+、CD3^+CD8^+显著更高(P<0.05),CD3^+CD4^+、CD4^+/CD8^+、NK细胞显著更低(P<0.05)。结论口腔黏膜病患者的外周血淋巴细胞亚群特点,能够反映出患者的免疫状态。
Objective To analyze the characteristics of peripheral blood lymphocyte subsets in oral mucosal disease.Methods A total of 90 patients with oral mucosal disease and 50 healthy physical examination subjects were selected as the research objects,which were divided into observation group A(49 cases of recurrent aphthous ulcer),observation group B(41 cases of oral licus planus)and control group(50 cases of healthy physical examination subjects),to detect peripheral lymphocyte subsets.Results Compared with the control group,the levels of CD3^+,CD3^+CD8^+in group A were signifi cantly higher(P<0.05),CD3^+CD4^+,CD4^+/CD8^+and CD3-CD19^+were signifi cantly lower(P<0.05),and the levels of CD3^+CD8^+in group B were signifi cantly lower(P<0.05).Compared with observation group B,observation group A had signifi cantly higher CD3^+,CD3^+CD8^+(P<0.05),and signifi cantly lower CD3^+CD4^+,CD4^+/CD8^+,and NK cells(P<0.05).Conclusion The characteristics of peripheral blood lymphocyte subsets in patients with oral mucosal disease can refl ect the immune status of the patients.
作者
洪有用
HONG Youyong(Department of Laboratory Medicine,Stomatological Hospital Affi liated to Xiamen Medical College,Xiamen 361000,China)
出处
《中国医药指南》
2020年第34期49-50,共2页
Guide of China Medicine
关键词
口腔黏膜病
外周血
淋巴细胞亚群
Oral mucosal disease
Peripheral blood
Lymphocyte subsets
