摘要
目的分析西安地区儿童青少年维生素D营养状况。方法采用前瞻性现况调查,检测在西安市儿童医院营养科就诊的3607例儿童青少年血清25-羟维生素D[25(OH)D]水平。分析不同性别、不同居住地区(城乡)、不同年龄段、不同营养状况的儿童青少年25(OH)D水平的差异。结果①共纳入3607例儿童青少年,男2255例,女1352例,年龄1月龄~17岁,平均(3.83±3.48)岁。②所有研究对象血清25(OH)D平均水平为(31.42±16.44)ng/mL,男孩为(30.95±16.42)ng/mL,女孩为(32.20±16.49)ng/mL,男孩与女孩间差异有统计学意义(t=2.24,P<0.05)。婴儿组25(OH)D平均为(38.14±15.43)ng/mL,幼儿组为(39.88±14.88)ng/mL,学龄前组为(26.61±13.38)ng/mL,学龄组为(18.08±10.97)ng/mL,各组间差异有统计学意义(F=480.20,P<0.05)。肥胖组25(OH)D平均为(17.60±11.52)ng/mL,营养不足组为(29.81±16.43)ng/mL,两组比较差异有统计学意义(t=9.13,P<0.05)。城市组25(OH)D平均为(29.12±15.05)ng/mL,农村组为(36.99±18.26)ng/mL,两组比较差异有统计学意义(t=13.38,P<0.05)。③缺乏率分析:维生素D总体缺乏率为50.07%(1806/3607),其中男孩为51.26%,女孩为48.08%,男女间差异无统计学意义(χ2=3.43,P>0.05)。婴儿组为30.35%,幼儿组为26.18%,学龄前组为63.81%,学龄组为88.54%,不同年龄组间差异有统计学意义(χ^2=922.50,P<0.05)。肥胖组为89.35%,营养不足组为52.30%,两组差异有统计学意义(χ^2=75.88,P<0.05)。城市组为57.86%,农村组为31.02%,两组间差异有统计学意义(χ^2=214.96,P<0.05)。④儿童肥胖程度与其血清25(OH)D水平相关性分析:二者呈负相关,有统计学意义(t=-2.50,P<0.05)。⑤不同月份25(OH)D水平变化趋势:9月份最高,为(51.26±8.58)ng/mL,2月份最低,为(24.61±16.39)ng/mL,夏秋季高于冬春季。结论西安地区儿童青少年维生素D营养状况较差,尤其是学龄阶段儿童、肥胖儿童、城市儿童,夏秋季优于冬春季。故应加强对大龄、肥胖儿童维生素D的检测
Objective To investigate vitamin D nutritional status of children and adolescents in Xi’an.Methods A prospective current situation survey was used to detect serum 25-hydroxy vitamin D[25(OH)D]level of the children and adolescents who visited to Department of Nutrition,Xi’an Municipal Children’s Hospital,and analyze the differences in serum 25(OH)D level of the children and adolescents in different situations including different genders,different resident areas(urban areas and rusal areas),different age stages and different nutritional states.Results(1)A total of 3 607 cases(2 255 males and 1 352 females) were included,aged from 1 month to 17 years old(average age:3.83±3.48 years).(2)The average serum 25(OH)D level of all children and adolescents was 31.42±16.44 ng/mL,that in boys was 30.95±16.42 ng/mL and that in girls was 32.20±16.49 ng/mL,there was a statistically significant difference between the two gender groups(t=2.24,P<0.05).The average serum 25(OH)D level in the infants group was 38.14±15.43 ng/mL,and that in the toddler group was 39.88±14.88 ng/mL,that in the preschool children group was 26.61±13.38 ng/mL,and that in the school-aged children group was 18.08±10.97 ng/mL,and the differences among the different age groups were statistically significant(F=480.20,all P<0.05).The average serum 25(OH)D level in the obese children group was 17.60±11.52 ng/mL,and that in the undernourished group was 29.81±16.43 ng/mL,the difference was statistically significant(t=9.13,P<0.05).The average serum 25(OH)D level in the urban children group was 29.12±15.05 ng/mL,and that in the rural children group was 36.99±18.26 ng/mL,the difference was statistically significant(t=13.38,P<0.05) too.(3) The total deficiency rate of vitamin D was 50.07%(1806/3607),of which that in boys was 51.26% and that in girls was 48.08%,and there was no significant difference in the deficiency rate between boys and girls(χ~2=3.43, P>0.05).The deficiency rate of vitamin D in the infants group,the toddlers group,the preschool chi
作者
刘瑞萍
熊凤梅
武海滨
LIU Ruiping;XIONG Fengmei;WU Haibin(Xi’an Municipal Children’s Hospital,Shaanxi Xi’an 710002,China)
出处
《中国妇幼健康研究》
2020年第12期1677-1681,共5页
Chinese Journal of Woman and Child Health Research
基金
西安市科技计划资助项目(2016052SF/YX08-5)
西安市科技计划资助项目(201805098YX6SF32-6)
西安市卫健委基金资助项目(J201602032)
陕西省科技厅基金资助项目(2020SF-002)
关键词
维生素D
儿童
青少年
营养状况
vitamin D
children
adolescent
nutritional status
