摘要
目的:观察早期应用血栓通注射液对中等严重程度脑梗死急性期卒中进展及预后的影响。方法:连续纳入脑梗死发病≤72h内患者60例,入院后一周之内较入院前NIHSS增加≥3分,头CT排除脑出血定义为进展性卒中;将患者随机分配为血栓通治疗组和常规治疗组。收集患者入院基线临床资料,观察治疗效2周后患者早期卒中进展情况以及3个月预后。结果:血栓通治疗组患者早期进展少于对照组(P=0.02),3个月mRS小于对照组,但未达到统计学差异(P=0.08)。结论:血栓通可降低急性期脑梗死进展,可能改善脑梗死预后,尚需大样本研究证实。
Objective:To observe the effect of early application of Xueshuantong injection on the progression and prognosis of stroke in the acute stage of moderate severity cerebral infarction.Methods:Sixty consecutive patients with cerebral infarction≤72h were included,and NIHSS increased by≥3 points within one week after admission.Head CT excluded cerebral hemorrhage and was defined as progressive stroke;patients were randomly assigned to Xueshuantong treatment group and routine therapy group.The baseline clinical data of patients admitted to the hospital were collected to observe the progress of early stroke and prognosis of patients after 2 weeks of treatment effect.Results:The early progression of the Xueshuantong treatment group was less than that of the control group(P=0.02),and the 3-month mRS was less than that of the control group,but the statistical difference was not reached(P=0.08).Conclusion:Xueshuantong can reduce the progress of acute cerebral infarction and may improve the prognosis of cerebral infarction,which needs to be confirmed by a large sample study.
作者
吴喜端
陈俊平
李剑
陈赟
Wu Xiduan(Department of Internal Medicine,Guicheng Hospital,Nanhai District,Foshan City,Foshan Guangdong 528000)
出处
《黑龙江医药》
CAS
2020年第4期810-812,共3页
Heilongjiang Medicine journal
关键词
脑梗死急性期
卒中进展
血栓通注射液
预后
Acute stage of cerebral infarction
stroke progression
Xueshuantong injection
prognosis
