摘要
目的探讨乳腺癌超声光散射成像参数血红蛋总量(HBT)与肿块体积大小及组织学分级间的关系,分析其对病情发展及预后评估的参考价值。方法回顾性分析135例术后病理确诊的乳腺癌患者信息,术前行超声光散射成像检查获得超声检查及光散射参数资料,分析不同体积大小、不同组织学分级间乳腺癌超声光散射成像参数(HBT)的差异。结果本组手术及病理诊断乳腺癌,以HBT≥140mol/L为临界值,术前光散射成像诊断符合率77.78%。HBT值在乳腺癌不同大小组之间的差异有统计学意义(P<0.05)若肿块直径≤20mm时,HBT值169.36±23.06,直径>20mm时,HBT值234.99±59.32,肿块体积较大时HBT值较高;HBT值在乳腺癌各组织学分级之间的差异比较有统计学意义(P<0.05)组织学分级I~Ⅲ级的HBT值149.60±16.21、185.97±32.00、245.21±57.09,肿块组织学分级较高时HBT值较高。结论乳腺超声光散射成像可为评估乳腺癌病情转归提供有价值的参考信息。
Objective To investigate the relationship among breast cancer HBT of diffused optical tomography,its diameter size and histological grade,and the value in assessing breast cancer progression and prognosis.Methods A retrospective analysis of 135 cases of breast cancer was curried out diffused optical tomography before operation,and finally confirmed by postoperative pathological fndings.The difference of HBT among breast cancer patients with different diameter size and histological grade was analyzed.Results For HBT≥140 for the diagnosis of malignant 1esions,the coincidence rate was 77.78%.There was significant difference of diffused optical tomography HBT in different diameter size group(P<0.05)if diameter size≤20,the value of HBT was 169.36±23.06,if diameter size>20,the value of HBT was 234.99±59.32.There was significant difference of diffused optical tomography HBT in different histological grade group(P<0.05)The HBT values of the histological grading I~Ⅲwere 149.60±16.21,185.97±32.00,245.21±57.09.Conclusion It can be inferred that HBT may become one of the indicators to assessing progression and prognosis of breast cancer.
作者
乔向彬
肖保军
黄丽
韩旭
马星宇
QIAO Xiangbin;XIAO Baojun;HUANG Li;HAN Xu;MA Xingyu(Department of Ultrasound, Daxing Teching Hospital, Capital Medical University, Beijing 102600, P.R.China)
出处
《医学影像学杂志》
2020年第7期1211-1213,1229,共4页
Journal of Medical Imaging
基金
北京市大兴区科技发展计划项目(编号:KT201802289)。
关键词
乳腺癌
光散射成像
组织学分级
超声检查
Among breast cancer
Diffused optical tomography
Histological grade
Ultrasonography