摘要
目的在慢性精神分裂症临床治疗中,对患者给予常规药物治疗的同时配合高频重复经颅磁刺激(rTMS)辅治,观察患者的治疗效果。方法纳入该院精神科临床收入并给予常规药物治疗的90例慢性精神分裂症患者为对象,纳入的时间段为2018年8月—2019年8月,根据不同的rTMS治疗模式分为3组,即甲组(n=30例,先给予5 Hz刺激,再给予10 Hz刺激)、乙组(n=30例,先给予10 Hz刺激,再给予5 Hz刺激)、丙组(n=30例,给予假刺激治疗),对比3组的效果。结果①甲组、乙组、丙组治疗的总有效率依次是93.33%、90.00%、76.67%,甲乙两组治疗的总有效率对比,差异无统计学意义(P>0.05),但均较丙组高(P<0.05)。②3组患者治疗前的MOCA评分、PANSS评分经对比,差异无统计学意义(P>0.05);治疗后甲乙两组对比差异无统计学意义(P>0.05),但均较丙组优(P<0.05)。结论 rTMS治疗慢性精神分裂症患者中,采取5 Hz、10 Hz交替治疗的效果显著,价值较高。
Objective In the clinical treatment of chronic schizophrenia,patients are given conventional medications and high frequency repetitive transcranial magnetic stimulation(rTMS)adjuvant therapy to observe the treatment effect of patients.Methods 90 patients with chronic schizophrenia who were included in the hospital's psychiatric clinical income and given conventional drug treatment were included in the period from August 2018 to August 2019.They were divided into 3 groups according to different rTMS treatment models.That is:group A(n=30 cases,first given 5 Hz stimulation,then 10 Hz stimulation),group B(n=30 cases,first given 10 Hz stimulation,then 5 Hz stimulation),group C(n=30 cases,given false stimulation treatment),compared the effects of the 3 groups.Results 1.The total effective rate of this treatment in group A,group B,and group C was 93.33%,90.00%,and 76.67%in turn.There was no statistically significant difference in the total effective rate of this treatment between group A and group B(P>0.05);But all were higher than group C(P<0.05).2.There was no statistically significant difference in the MOCA score and PANSS score of the three groups before treatment(P>0.05);there was no difference between the two groups after treatment,but they were better than the C group(P<0.05).Conclusion In the treatment of patients with chronic schizophrenia,the effect of alternating 5 Hz and 10 Hz treatment with rTMS is significant.
作者
陈青
CHEN Qing(Second Ward,Pingyi County Psychiatric Hospital,Linyi,Shandong Province,273300 China)
出处
《系统医学》
2020年第11期34-36,共3页
Systems Medicine
