摘要
目的观察麻杏石甘汤联合阿奇霉素治疗肺炎支原体感染致小儿肺炎喘嗽风热闭肺证的临床效果。方法100例患儿随机分为对照组(n=50)及观察组(n=50)。对照组给予阿奇霉素治疗,观察组给予麻杏石甘汤联合阿奇霉素治疗。比较2组的治疗效果及炎症指标水平变化。结果观察组中医证候总有效率,临床症状体征消失及住院治疗时间均优于对照组(P<0.05);治疗后2组中医主症积分及炎症指标水平均下降,且观察组小于对照组(P<0.05);2组不良反应对比无统计学差异(P>0.05)。结论应用麻杏石甘汤联合阿奇霉素治疗肺炎支原体感染致肺炎喘嗽风热闭肺证患儿,疗效显著,能降低相关炎症指标,安全性高。
Objective To the clinical effect of Maxingshigan Decoction combined with azithromycin in the treatment of mycoplasma pneumoniae infection in children with pneumonia caused by wheezing heat and closing lung syndrome.Methods 100 children are randomLy divided into control group(n=50)and observation group(n=50).The control group is treated with azithromycin,and the observation group is treated with Maxingshigan Decoction combined with azithromycin.The therapeutic effect and inflammatory index level of the two groups are compared.Results The total effective rate of TCM syndrome,the disappearance of clinical symptoms and signs and the length of hospitalization in the observation group are better than those in the control group(P<0.05).After treatment,the main symptom score and inflammatory index level of the two groups decreased,and the observation group is smaller than the control group(P<0.05).There is no significant difference in the adverse reactions between the two groups(P>0.05).Conclusion The application of Maxingshigan Decoction combined with azithromycin in the treatment of children with mycoplasma pneumoniae infection caused by pneumonia with wheezing heat and pulmonary closure syndrome has significant efficacy,can reduce the related inflammatory indicators,high safety.
作者
毛庆东
顾敏勇
潘彪
陈启锋
MAO Qing-dong;GU Min-yong;PAN Biao;CHEN Qi-feng(Department of Pediatrics,Wuhu Hospital of Traditional Chinese Medicine,Wuhu 241002,China)
出处
《现代中药研究与实践》
CAS
2020年第3期65-68,共4页
Research and Practice on Chinese Medicines
基金
芜湖市卫计委课题研究项目(芜卫科教[2019]5号)。
关键词
麻杏石甘汤
阿奇霉素
肺炎支原体
小儿
肺炎喘嗽
风热闭肺证
疗效
Maxingshigan decoction
azithromycin
mycoplasma pneumoniae
children
pneumonia wheeze
wind heat closed lung syndrome
the curative effect
