摘要
盆腔器官脱垂(pelvic organ prolapse,POP)是多种病因导致的盆底支持系统薄弱,女性生殖系统和相邻的脏器发生位置异常,形成子宫脱垂、阴道前后壁膨出等临床疾病。本文对疾病的流行病学及病因、目前治疗手段进行了整体概述,并着重对发病基础机制和间充质干细胞(mesenchymal stem cells,MSCs)在疾病中的应用前景进行了详细的阐述。
Pelvic organ prolapse( POP) is caused by a variety of causes,such as weak pelvic floor support system,abnormal location of female reproductive system and adjacent organs,uterine prolapse,anterior and posterior vaginal wall prolapse and other clinical diseases. In this paper, the epidemiology,etiology and current treatment of the disease were summarized,and the basic pathogenesis and the application prospect of mesenchymal stem cells( MSCs) in the disease were described in detail.
作者
周懿雯
平毅
ZHOU Yiwen;PING Yi(Shanxi Medical University,Taiyuan 030000,Shanxi,China;Department of Obstetrics and Gynecology,the Second Hospital of Shanxi Medical University,Taiyuan 030000,Shanxi,China)
出处
《中国临床药理学与治疗学》
CAS
CSCD
2020年第5期595-600,共6页
Chinese Journal of Clinical Pharmacology and Therapeutics
基金
山西省自然科学基金(201901D111366)。
关键词
盆腔脏器脱垂
间充质干细胞
机制
治疗
pelvic organ prolapse
mesenchymal stem cells
pathogenesis
treatment
