摘要
目的明确盆腔脏器脱垂(POP)在中国城市女性中的患病率及危险因素。方法对中国6大地区(东北、西北、西南、华南、华东及华中)城市中20岁以上女性开展POP的流行病学调查,研究采用分层、整群随机抽样的方法,通过问卷调查,POP的诊断标准为脱垂症状问卷回答至少一项阳性并且通过盆腔脏器脱垂的量化分期(POP-Q)分度为Ⅱ度及以上的脱垂。结果29613例城市女性纳入分析,城市女性POP的整体患病率为9.67%(2864/29613),70岁以上人群患病率高达26.11%(727/2784)。多因素回归分析结果显示,超重[调整后比值比(AOR=1.56),95%可信区间(95%CI1.42~1.72)]、肥胖(AOR=1.74,95%CI1.48~2.03)、便秘(AOR=2.05,95%CI1.82~2.32)、慢性咳嗽(AOR=1.70,95%CI1.44~2.02)、妇科疾病(AOR=2.08,95%CI1.89~2.29)及躯体疾病(AOR=1.27,95%CI1.15~1.41)是POP的危险因素。而未产(AOR=0.12,95%CI0.060~0.22)和剖宫产(AOR=0.55,95%CI0.47~0.64)是POP患病的保护因素。结论中国城市女性POP的患病率着年龄增加而增加;超重、肥胖、便秘、咳嗽、妇科疾病及躯体疾病是POP患病的危险因素;未产及剖宫产是POP患病的保护因素。
Objective This study aimed to assess the prevalence and factors associated with pelvic organ prolapse(POP)in a representative sample of Chinese urban women.MethodsA total of 29613 Chinese urban women were recruited to this cross-sectional study between February 2014 and March 2016.The prevalence of POP,defined as any stageⅡor higher POP resulting in symptoms,was assessed using questionnaires and physical examinations.Multivariable logistic regression was used to assess factors associated with POP.Results 2 864 of 29 613 women(9.67%)had POP.The prevalence of POP increased with age ranging from 1.23%(82/6 646)of women aged between 20 and 29 years to 26.11%(727/2 784)for those aged 70 years or older(P<0.000 1).Overweight and obese women were more likely to have POP than normal weight women[AOR=1.56,95%CI 1.42-1.72 vs AOR=1.74,95%CI 1.48-2.03].In the multivariate analysis,the independent risk factors were cough(AOR=1.70,95%CI 1.44-2.02),constipation(AOR=2.05,95%CI 1.82-2.32),physical disease(AOR=1.27,95%CI 1.15-1.41),and gynecological diseases(AOR=2.08,95%CI 1.89-2.29).Nulliparous(AOR=0.12,95%CI 0.06-0.22)and caesarean section(CS)(AOR=0.55,95%CI 0.47-0.64)were protective factors for POP.Conclusions POP affects nearly 10%of women in Chinese urban region.The prevalence of POP increases significantly with age.The independent risk factors for POP are body mass index,cough,constipation,physical disease and gynecological diseases.Nulliparous and CS are protective factors for POP.
作者
李志毅
朱兰
徐涛
刘青
李兆艾
龚健
王玉玲
汪俊涛
赖婷
吴玲
郎景和
Li Zhiyi;Zhu Lan;Xu Tao;Liu Qing;Li Zhaoai;Gong Jian;Wang Yuling;Wang Juntao;Lai Ting;Wu Ling;Lang Jinghe(Department of Gynecology and Obstetrics,Peking Union Medical College Hospital,Peking Union Medical College,Beijing 100730,China;Department of Epidemiology and Statistics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences and School of Basic Medicine,Peking Union Medical College,Beijing 100005,China;Department of Gynecology and Obstetrics,Maternal and Child Health Hospital of Gansu Province,Lanzhou 730050,China;Department of Gynecology and Obstetrics,Childrens Hospital of Shanxi Province,Taiyuan 030013,China;Department of Gynecology and Obstetrics,Maternal and Child Health Hospital of Wuxi,Wuxi 214002,China;Department of Gynecology and Obstetricsf Maternal and Child Health Hospital of Foshan,Foshan 528000,China;Department of Gynecology and Obstetrics,Maternal and Child Health Hospital of Guiyang,Guiyang 550001,China;Department of Gynecology and Obstetrics,Maternal and Child Health Hospital of Huaian,Huaian 223002,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2019年第11期857-861,共5页
National Medical Journal of China
关键词
流行病学调查
盆腔脏器脱垂
中国城市
患病率
Epidemiology
Pelvic organ prolapse
Chinese urban region
Prevalence risk
