摘要
目的:调查分析中国三级甲等医院皮肤科门诊湿疹慢性期患者一般情况、临床特征和流行病学特点,并分析其相关因素。方法:对2014年7月1日-9月30日在中国大陆15个省市的39家三甲医院皮肤科门诊就诊并诊断为湿疹慢性期患者的问卷调查结果进行分析。结果:本调查中分期诊断的湿疹患者共1991例,其中湿疹慢性期1223例(61.43%,1223/1991);男女比例相当(1∶1),平均年龄(40.44±18.67)岁,以20~39岁(35.81%)、40~59岁(31.89%)为主;病程(3.31±6.29)年,以0~1年(44.48%)为主;瘙痒以轻度(42.68%)、中度(41.37%)为主;既往有过敏性皮肤病史(8.01%)、皮肤干燥史(12.67%)、屈侧皮炎史(3.43%)及婴儿湿疹史(5.15%),临床可疑细菌感染为8.18%;皮损部位构成前五位为小腿35.49%、上肢34.01%、手26.57%、大腿25.10%及腰部18.48%;地理位置分组北纬40~45°构成比最低(3.71%);经济状况分组北上广组构成比低于其他地区组(9.92%vs. 15.90%,P<0.001)。结论:湿疹慢性期为皮肤科常见问题,中青年高发,易累及四肢及腰部,轻中度瘙痒为主,并发细菌感染率低,高纬度地区构成比更低,经济因素可能对其有影响。
Objectives: To investigate the clinical features and epidemiological characteristics of chronic eczema, and their associated factors in outpatients of dermatology clinics. Methods: Using a questionnaire, a multicenter cross-sectional study was conducted in outpatients with chronic eczema in 39 grade 3 A hospitals from 15 provinces from July 1 to September 30,2014. Results: A total of 1223 out of 1 991(61.43%) of patients with eczema were chronic eczema, with a male to female ratio of 1∶1 and mean age of(40.44±18.67) years. Patients aged 20~39 years and 40~59 years accounted for 35.81% and31.89%, respectively. The average course of disease was(3.31±6.29) years, while 44.48% of patients were with a course of1 year or less. Majority of patients experienced mild to moderate pruritus(mild: 42.68%, moderate: 41.37%). Some patients had a history of other disorders such as allergic disease(8.01%), dry skin(12.67%), flexural dermatitis(3.43%), infantile eczema(5.15%) and clinically suspected bacterial infection(8.18%). The commonly involved sites included the trunk(35.49%), upper limbs(34.01%), hands(26.57%), thighs(25.10%) and waist(18.48%). The lowest rate of chronic eczema was found in subjects residing at N 40°~45° such as Liaoning province(3.71%), and economically well-developed areas, including Beijing, Shanghai and Guangzhou(9.92% vs. 15.90% in other areas, P<0.001). Conclusions: Chronic eczema is a common disease in dermatology, and mainly involves the extremities and the waist with mild to moderate pruritus in young and middle-aged subjects. Complication with bacterial infection is not common. Prevalence of chronic eczema is low in high latitude and economically well-developed regions.
作者
王鑫
石晓东
高飞
李邻峰
WANG Xin;SHI Xiao-dong;GAO Fei;LI Lin-feng(Department of Dennaiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2020年第1期10-13,共4页
Journal of Clinical Dermatology
关键词
临床特点
湿疹慢性期
流行病学
横断面研究
clinical feature
chronic eczema
epidemiology
cross-sectional study
