摘要
目的 探讨慢性湿疹(chronic eczema, CE)患者述情障碍、焦虑的程度与生活质量的相关性。方法 随机抽取马鞍山市人民医院皮肤科的200例慢性湿疹患者及202例健康人群作为对照组进行分析,运用湿疹面积和严重指数(eczema area and severity index, EASI)、睡眠和瘙痒数字评分量表(visual analog scale for sleep and itch, VAS)、多伦多述情障碍自评量表(Toronto alexithymia scale, TAS)-26、焦虑自评量表(self-rating anxiety scale, SAS)、皮肤病生活质量指数(dermatology life quality index, DLQI)进行症状量化评分。利用独立样本t检验和卡方检验,对两组人群的述情障碍、焦虑、生活质量量表得分进行分析比较,利用多元有序Logistic回归分析慢性湿疹患者生活质量相关的因素。结果 慢性湿疹组TAS-26得分为66.90±11.37,显著高于对照组得分(59.02±10.07)(P<0.01)。慢性湿疹组SAS平均分为37.08±7.94,显著高于对照组SAS平均分(33.78±7.08)(P<0.01)。多元有序Logistic回归分析结果显示,低文化程度(初中:OR=2.86, 95%CI:1.31~6.25)、有焦虑(OR=3.40, 95%CI:1.39~8.29)、瘙痒分值高(≥7分:OR=14.99, 95%CI:4.01~55.98;4~6分:OR=2.06, 95%CI:1.00~4.25)与慢性湿疹患者DLQI评分呈正相关。结论 慢性湿疹患者较健康人群更易出现述情障碍和焦虑人格特征。低文化程度、焦虑以及瘙痒分值高是生活质量下降的危险因素。
Objective To explore the relationship between alexithymia,anxiety and quality of life in patients with chronic eczema(CE).Methods A total of 200 patients with chronic eczema and 202 healthy subjects as control group were randomly selected from the Department of Dermatology,Ma'anshan People's Hospital,for analysis.The eczema area and severity index(EASI),sleep and pruritus digital scores scale(VAS),Toronto alexithymia scale(TAS)-26,self-rating anxiety scale(SAS),and dermatology life quality inventory(DLQI)were used to quantify symptom scores.Independent sample t-tests and chi-square tests were used to analyze and compare the scores of alexithymia,anxiety,and the quality of life scale between the two groups.Multiple ordinal Logistic regression was used to analyze the factors for quality of life in patients with chronic eczema.Results The TAS-26 score of the CE group was 66.90±11.37,which was significantly higher than that of the control group(59.02±10.07)(P<0.01).The average SAS score of the CE group was 37.08±7.94,which was significantly higher than that of the control group(33.78±7.08)(P<0.01).Multiple ordinal Logistic regression analysis showed that patients with low education level(middle school OR=2.86,95%CI:1.31-6.25),anxiety(OR=3.40,95%CI:1.39-8.29),and high score of pruritus(≥7:OR=14.99,95%CI:4.01-55.98;4-6:OR=2.06,95%CI:1.00-4.25)were positively associated with the DLQI score in chronic eczema patients.Conclusion Patients with chronic eczema are more likely to have alexithymia and anxiety personality characteristics than healthy people.Low education level,anxiety,and high score of pruritus are risk factors for the decline of quality of life.
作者
程晓旭
黄茂欣
唐的木
肖风丽
CHENG Xiaoxu;HUANG Maoxin;TANG Dimu;XIAO Fengli(Department of Dermatology,the First Affiliated Hospital of Anhui Medical University,Institute of Dermatology,Anhui Medical University,Hefei 230032,China;Department of Dermatology,Ma'anshan People's Hospital,Ma'anshan 243000,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2023年第12期1378-1384,共7页
The Chinese Journal of Dermatovenereology
基金
国家自然科学基金项目(81972926)。
