摘要
目的探讨剖宫产术后子宫瘢痕妊娠(CSP)的预处理方法。方法对四川大学华西第二医院生殖内分泌科收治的Ⅱ型和Ⅲ型CSP患者90例的临床资料进行回顾性分析,所有患者入院后均行子宫动脉栓塞术(UAE),并根据是否行缩宫素预处理分为两组:研究组即缩宫素预处理组:在进入手术室、麻醉满意后,行清宫术前宫颈局部注射缩宫素10U,同时予缩宫素10U加入到5%GS 500mL维持静脉通道。对照组未给予缩宫素预处理,直接行清宫术。分析两组患者的出血量、球囊压迫率、开腹或腹腔镜手术率、术后血β-hCG恢复正常时间、住院费用。结果研究组CSP患者的术中出血量明显少于对照组,且研究组CSP患者的球囊压迫率、开腹或腹腔镜手术率、住院费用均明显低于对照组,差异有统计学意义(P<0.05);两组患者术后血β-hCG恢复正常时间差异无统计学意义(P>0.05)。结论对Ⅱ型和Ⅲ型CSP行UAE后,于清宫术前给予缩宫素行预处理,可明显减少手术出血量、降低球囊压迫率及开腹或腹腔镜手术率,更有利于CSP患者的恢复。
Objective To investigate the pretreatment of cesarean scar pregnancy(CSP).Methods A retrospective analysis was done on the clinical data of 90 patients with CSP of typeⅡandⅢadmitted to the Department of Reproductive Endocrinology of West China Second University Hospital of Sichuan University.All those patients were treated with uterine artery embolization(UAE)after admission and divided into the experiment group and control group according to the pretreatment methods.The experiment group was pretreated with oxytocin.After entering the operating room and successfully anesthetized,the patients of the experiment group were given the local injection with oxytocin 10 Uat the cervix before dilatation and curettage(D&C)and oxytocin10 U was added to 5%GS 500 mL to maintain the venous access.The control group was not given the oxytocin pretreatment before D&C.The amount of surgical blood loss,balloon compression rate,rates of laparotomy or laparoscopic surgery,β-HCG recovery time after operation and hospitalization cost were analyzed in the two groups.Results The blood loss of the experiment group was significantly less than that of the control group(P<0.05).The balloon compression rate,rates of laparotomy or laparoscopic surgery,and hospitalization cost were significantly less in the experiment group than in the control group(P<0.05).There was no significant difference in theβ-HCG recovery time after operation between the two groups(P>0.05).Conclusion The pretreatment with oxytocin before D&C can significantly reduce the amount of surgical blood loss,balloon compression rate and rates of laparotomy or laparoscopic surgery in the patients with CSP of typeⅡandⅢafter UAE,which is beneficial for the patients’recovery.
作者
王祉麟
谭菲
张丹
Wang Zhilin;Tan Fei;Zhang Dan(Department of Obstetrics and Gynecology,West China Second University Hospital of Sichuan University,Chengdu 610041,China;Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,Chengdu 610041,China)
出处
《成都医学院学报》
CAS
2020年第1期102-104,108,共4页
Journal of Chengdu Medical College
