摘要
目的分析2型糖尿病(T2DM)患者视网膜病变(DR)患病率及其相关因素。方法对3404例2型糖尿病住院患者进行回顾性研究,根据眼科会诊结果,将患者分为3组,其中非DR组(A组/NDR组)2562例,DR非增殖期组(B组/NPDR组)716例,DR增殖期组(C组/PDR组)126例。得出DR的患病率,比较3组患者之间临床资料及临床指标的异同,及其与DR的相关性。结果2型糖尿病患者DR患病率达24.7%,与甘油三酯(OR=1.110,P=0.000)、糖化血红蛋白(HbA 1c)(OR=1.087,P=0.000)、血尿酸(OR=1.003,P=0.000)、病程(OR=1.002,P=0.000)相关。结论2型糖尿病患者DR患病率为24.7%,高血脂、高血糖、高尿酸血症、病程长为DR的独立危险因素。早期发现糖尿病、早期治疗糖尿病、积极控制血糖血脂血尿酸,对于减少DR的发生及延缓DR的发展意义重大。
Objective To analyze the incidence and related factors of diabetic retinopathy(DR)in patients with type 2 diabetes mellitus(T2DM).Methods A total of 3404 inpatients with T2DM were studied retrospectively.According to the results of ophthalmic consultation,the patients were divided into three groups,including 2562 cases ofnon-DR group(group A/NDR),716 cases of non-proliferative DR group(group B/NPDR),and 126 cases of proliferative DR group(group C/PDR).The incidence of DR was obtained,then the differences and similarities in clinical data and clinical indicators among three groups were compared,as well as the prevalence of DR.Results The incidence rate of DR in T2DM patients was 24.7%,which was correlated associated with triglyceride(OR=1.110,P=0.000),glycosylated hemoglobin(HbA 1c)(OR=1.087,P=0.000),serum uric acid(OR=1.003,P=0.000),course of disease(OR=1.002,P=0.000).Conclusion The incidence rate of DR in T2DM patients was 24.7%,and hyperlipidemia,hyperglycemia,hyperuricemia,long course of disease were independent risk factors for DR.Early detection and treatment of diabetes,active control of blood glucose,lipids and uric acid are of great significance to reduce the occurrence of DR and delay the development of DR.
作者
江旭
刘尚全
Jiang Xu;Liu Shangquan(Department of Endocrinology,the Third Affiliated Hospital of Anhui Medical University,Hefei 230000,China)
出处
《临床荟萃》
CAS
2020年第1期54-58,共5页
Clinical Focus
基金
国家自然科学基金资助项目——淫羊霍次苷Ⅱ调控OPG表达及机制研究(30840106)
