摘要
帕金森病是中老年人常见的慢性进展性神经系统变性疾病,中晚期患者因服用左旋多巴所导致的异动症(LID)几乎不可避免。基于"阳虚风动"理论探讨LID的发病机制、特点以及症状,认为LID病位在肝、肾,与脾相关;病理性质以阳虚为主,与风、痰、瘀相关。由于脏腑阳气亏损,脉络空虚,经络、筋脉失温,导致肢体失任,内风由此而生。LID的治疗应以温肾养肝、温阳熄风为基本治则,在临床应用中可结合健脾、化痰、行瘀等灵活遣方用药。
Parkinson′s disease is a common chronic progressive neurodegenerative disease in middle-aged and elderly people, and the occurrence of Levodopa-induced dyskinesia(LID) in the middle and late stage is almost inevitable. In this paper, the pathogenesis, characteristics and symptoms of dyskinesia of Parkinson′s disease were discussed based on the theory of "stirring wind due to yang deficiency". The location of the disease was mainly liver, kidney and spleen. The pathological features were mainly yang deficiency, and was related to wind, phlegm and blood stasis. Due to the deficiency of yang, hollow and deficienct meridians and collaterals, tendons and veins are lack of nourishment, resulting in internal wind formation and dyskinesia. Warming the kidney and nourishing the liver and warming yang to extinguish wind should be the basic treatment principle for the treatment of LID. In clinical application, other flexible prescriptions such as invigorating the spleen, resolving phlegm and removing blood stasis can be considered.
作者
陆艳
徐成成
唐莉莉
梁艳
赵杨
LU Yan;XU Chengcheng;TANG Lili;LIANG Yan;ZHAO Yang(Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing,210001)
出处
《中医杂志》
CSCD
北大核心
2020年第2期123-125,共3页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81804022)
南京市中医药转化医学基地转化医学项目(ZHCX201806)
南京市名老中医专家传承工作室建设项目(宁卫中医[2017]8号)
关键词
阳虚风动
帕金森病
异动症
颤症
温肾养肝
stirring wind due to yang deficiency
Parkinson′s disease
levodopa-induced dyskinesia
tremor warming the kidney and nourishing the liver
