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痰液标本细菌培养及药敏试验对肺癌患者姑息疗法后肺部感染抗菌药物合理使用的影响 被引量:4

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摘要 目的:分析痰液标本细菌培养及药敏试验对肺癌患者姑息治疗后肺部感染的病原菌分布及其对抗菌药物的耐药性,为临床合理使用抗菌药物提供参考。方法:选取2017年10月-2019年4月间收治的肺癌患者姑息治疗后肺部感染83例资料,统计其痰液标本细菌培养与药敏试验结果,分析其肺部感染致病菌分布及其对不同抗菌药物的耐药性。结果:83例肺部感染患者中,痰液标本中培养出病原菌157株,其中革兰阴性菌92株(占58.60%)、革兰阳性菌54株(占34.39%)和真菌11株(占7.01%);主要革兰阴性菌对阿米卡星、亚胺培南的耐药性较低,而主要革兰阳性菌对万古霉素耐药性较低。结论:通过痰液标本细菌培养及药敏试验,明确肺癌姑息治疗后肺部感染致病菌构成及耐药程度,为临床科学、合理用药提供参考依据;在充分考虑患者耐受程度、过敏反应、不良反应与化疗药物相互作用等前提下,选用阿米卡星、亚胺培南、万古霉素作为经验用药。
作者 侯晶晶
出处 《抗感染药学》 2019年第11期1877-1880,共4页 Anti-infection Pharmacy
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