摘要
目的探讨妊娠晚期静脉血栓栓塞症发生的危险因素,并针对性提出改善措施。方法选取2017年1月至2019年1月在唐山市妇幼保健院产前门诊建立健康档案规律产检妊娠晚期的孕妇资料进行分析,收集孕妇年龄、体质量指数、吸烟史、饮酒史、合并疾病及产科危险因素等资料,分析其与静脉血栓栓塞症发生的相关性。结果 13 472例孕妇中发生静脉血栓栓塞症54例,发生率为0.4%,其中深静脉血栓为51例,3例为深静脉血栓合并肺栓塞。单因素分析显示,有深静脉血栓和无深静脉血栓孕妇饮酒史、静脉血栓家族史、妊娠期贫血、孕期感染、妊娠期脂肪方面比较,差异无统计学意义(P>0.05);有深静脉血栓和无深静脉血栓孕妇在年龄、孕前体质量指数、孕期增重、吸烟史、下肢组织感染史、产次、盆腔感染史、下肢静脉曲张、流产史、胎儿数量、个人活动、妊娠期糖尿病、妊娠期高血压、子痫前期、妊娠剧吐、胎盘早剥、羊水过少等方面比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示年龄≥35岁、双胎或多胎、卧床久坐、妊娠期糖尿病、子痫前期是影响妊娠晚期深静脉血栓栓塞症发生的独立危险因素,差异有统计学意义(P<0.05)。结论妊娠晚期静脉血栓栓塞症发生率较高,其发生受多种因素影响,临床应给予重点关注,并进行针对性预防,以降低妊娠晚期静脉血栓栓塞症的发生率。
Objective To explore the risk factors of venous thromboembolism in the third trimester of pregnancy, and to propose improvement measures. Methods The data of third trimester pregnant women in Tangshan Maternal and Child Health Hospital from January 2017 to January 2019 were selected for statistical analysis. The correlation between maternal age, body mass index, personal history, complications and obstetric risk factors and the occurrence of venous thromboembolism was observed. Results There were 54 cases of venous thromboembolism in 13 472 pregnant women, the incidence of which was 0.40 %, including 51 cases of deep venous thrombosis and 3 cases of deep venous thromboembolism with pulmonary embolism. The univariate analysis showed that there was no significant difference in drinking history, family history of venous thrombosis, pregnancy anemia, pregnancy infection and pregnancy fat among pregnant women with or without DVT(P>0.05);there was significant difference in age, body mass index before pregnancy, weight gain during pregnancy, smoking history, history of lower extremity tissue infection, parity, pelvic infection history, lower extremity varicose veins, history of abortion, number of fetuses, personal activities, gestational diabetes mellitus, gestational hypertension, preeclampsia, hyperemesis gravidarum, placental abruption and oligohydramnios among pregnant women with or without DVT(P<0.05).Multivariate logistic regressisn analysis showed that age≥35 years old, twin or multiple births, sedentary in bed, gestational diabetas, and preeclampsia were independent risk factors for the developrnemt of deep venous thromboemlism in late pregnancy. The difference was statistically significant(P<0.05). Conclusion The incidence of venous thromboembolism in the third trimester of pregnancy is relatively high. The occurrence of venous thromboembolism is affected by many factors. Clinicians should pay attention to it and make targeted prevention to reduce the incidence of venous thromboembolism in the third trimeste
作者
闫莉丽
张春梅
杨涛
YAN Li-li;ZHANG Chun-mei;YANG Tao(Department of Obstetrics and Gynaceology,Tangshan Maternal and Child Health Hospital,Tangshan Hebei 063000,P. R. China;Department of Vascular Surgery,Tangshan GongRen Hospital,Tangshan Hebei 063000,P. R. China)
出处
《中国计划生育和妇产科》
2019年第10期92-96,共5页
Chinese Journal of Family Planning & Gynecotokology
关键词
妊娠晚期
静脉血栓栓塞
危险因素
late pregnancy
venous thromboembolism
risk factors
