摘要
目的:探讨孕妇年龄与妊娠高危因素、妊娠结局的关系。方法:通过对2015年1月1日至2016年10月31日期间,在南方医科大学珠江医院分娩的所有产妇作为研究分析对象,按年龄划分为4组,≤24岁组543例(13.76%)、25~29岁组1648例(41.18%)、30~34岁组1208例(30.61%)、≥35岁组547例(13.86%)。统计4组不同年龄孕妇妊娠合并症、并发症的发生率和妊娠结局,将25~29岁组设为对照组(OR=1),进行二元Logsitic回归分析年龄与妊娠合并症、并发症及妊娠结局等的相关性。结果:在年龄>30岁孕妇中,不良孕产史、本次辅助生殖助孕妊娠、妊娠合并子宫肌瘤、妊娠期糖尿病、瘢痕子宫OR值均>1,且随年龄组增加,OR值递增。前置胎盘、多胎妊娠、产后出血,分娩巨大儿、低体质量儿、早产儿,在年龄≥35岁组中OR值>1。子痫前期中年龄≤24岁组、≥35岁组OR值均>1。在30~34岁组出生缺陷儿的OR值>1。结论:对不同年龄孕妇,要有针对性地采取围生期检查及保健工作,及时对高危孕妇进行干预,积极治疗相关合并症,预防并发症,适时选择最佳分娩方式,综合保障母婴健康。
Objective： Explore the relationship among maternal age, risk factors and pregnancy outcomes. Methods：All childbirth women in Zhujiang hospital of Southern medical university from January 1,2015 to October 31,2016 were recruited and divided into 4 groups according to age ：543 cases（13.76% ） in ≤24 years old,1648 cases in 25 -29 years old （41.18%）, 1208 cases in 30 - 34 years old （30.61% ）, 547 cases in ≥ 35 years old （13.86%）. Data of 4 groups about pregnancy complications and outcomes were collected. Set group 20 -29 years old as the control group（ OR = 1 ）. Use X2 test and binary-logistic regression to analyze data. Results ：The elder groups had a higher rate in pregnancy complications and abnormal neonatal situation compared to other age groups. The group ~〈24 years old and the group in 30 -34 years old had a higher risk on preeclampsia and birth defects, respectively. In the group age 〉30 years old, OR 〉 1 in following items ：the histories of abnormal pregnan- cy,IVF-ET postoperative, pregnancy with uterine fibroid, gestationaldiabetes and scar uterus, and with the in- crease of age,the OR value increased. In the group age 〉50 years old, OR 〉 1 in placenta previa, multiple preg- nancy and postpartum hemorrhage, macroscopic delivery and low birth weight, premature infants. In the group 30 -34 years old, OR 〉 1 in birth detects. Conclusions： Different specific targeted examinations and health care work should be taken to pregnant women according to the age. Intervention for high risk factors, active treatment related to congenital disorders and prevention of complications are needed to timely choose the best way of deliv- ery,comprehensive security maternal and child health.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2017年第9期692-696,共5页
Journal of Practical Obstetrics and Gynecology
基金
南方医科大学临床研究培育项目(编号:LC2016PY035)
关键词
年龄
高危因素
妊娠期合并症
妊娠期并发症
妊娠结局
Age
High risk factor
Complication of pregnancy
Pregnancy complications
Pregnancy outcome
