摘要
目的调查运动认知功能减退综合征(MCR)的检出情况,并探讨可能的危险因素。方法横断面研究,纳入2014年10月至2018年9月在浙江医院老年病科就诊患者429例,采集一般情况资料及功能评估资料(包括跌倒史、视力障碍及听力障碍、抑郁情绪、认知功能和步速评估)。根据MCR诊断标准筛选出MCR患者,并采用多因素Logistic回归分析模型分析相关危险因素。结果17例(4.0%)患者符合MCR诊断标准。MCR患者肥胖、多重用药、脑血管疾病、听力障碍、抑郁症状和步速减慢比例均高于非MCR患者(均P<0.05);与非MCR患者比较,MCR患者简易精神状态检查(MMSE)得分更低(P<0.01)。矫正相关混杂因素后,多因素Logistic回归分析结果显示肥胖(OR=3.74,95%CI:1.14~12.23,P<0.05)和抑郁症状(OR=5.79,95%CI:1.76~19.06,P<0.01)是发生MCR的危险因素。结论MCR在老年患者并不少见,肥胖和抑郁症状与MCR风险增加密切相关。
To investigate the detection rate of motoric cognitive risk syndrome(MCR)and explore the possible risk factors. Methods A total of 429 elderly patients from geriatric department of Zhejiang Hospital from October 2014 to September 2018 were recruited in the cross-sectional study.General information and functional assessment including fall history, self-reported visual impairment and hearing impairment, depressive symptom, cognitive function and gait speed were collected.Patients with MCR were screened out according to the MCR diagnostic criteria.Multiple logistic regression analysis was used to analyze the associated risk factors. Results Seventeen patients(4.0%)met the MCR diagnostic criteria.The proportions of obesity, polypharmacy, cerebral vascular diseases, self-reported hearing impairment, depressive symptoms and slow gait were higher in MCR patients than in non-MCR patients(P<0.05). Compared with non-MCR patients, MCR patients had lower mini mental state examination(MMSE)scores(P<0.01). After adjusting for associated confounding factors, multiple logistic regression analysis showed obesity(OR=3.74, 95%CI: 1.14-12.23, P<0.05)and depressive symptoms(OR=5.79, 95%CI: 1.76-19.06, P<0.01)were risk factors for MCR. Conclusions MCR is not uncommon in elderly patients.Obesity and depressive symptoms are closely associated with an increased risk of MCR.
作者
沈珊珊
褚娇娇
杨影红
曾幸坤
徐立宇
刘子夏
陈凌燕
陈旭娇
Shen Shanshan;Chu Jiaojiao;Yang Yinghong;Zeng Xingkun;Xu Liyu;Liu Zixia;Chen Lingyan;Chen Xujiao(Geriatric Department, Zhejiang Hospital, Hangzhou 310013, China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2019年第6期620-623,共4页
Chinese Journal of Geriatrics
基金
浙江省医学重点创新学科(老年逆龄医学)资助
浙江省医药卫生科技计划项目(2016ZDB001、2018ZH001)
浙江医院“530”人才培养工程项目(2018-30-09).
关键词
认知
步态
痴呆
危险因素
Cognition
Gait
Dementia
Risk factors
