摘要
脓毒症是一种临床常见的危重疾病,具有发病率高、发病机制复杂、病情严重和病死率高的特点。其本质为由感染引发的宿主免疫反应失调,并表现为由此导致的威胁生命的器官功能障碍的临床综合征。自1991年脓毒症的概念出现至今,脓毒症一直是重症医学领域的一个热点和前沿问题。目前,临床常用的脓毒症治疗方法主要有液体治疗与复苏、抗感染治疗和血流动力学支持。未来,应用抗菌肽、免疫疗法、中医中药治疗等治疗方法可能成为脓毒症治疗的新方向。
Sepsis is a common critical disease in clinic,which has the characteristics of high incidence,complicated pathogenesis,serious condition and high fatality rate.Its essence is the imbalance of host immune response caused by infection,which is manifested as a clinical syndrome of life-threatening organ dysfunction.Since the concept of sepsis emerged in 1991,sepsis has been a focus and frontier issue in the field of intensive medicine.At present,liquid therapy and resuscitation,anti-infection therapy and hemodynamic support are commonly used in clinical treatment of sepsis.In the future,the application of antimicrobial peptides,immunotherapy,traditional Chinese medicine treatment and other treatment methods may become new directions of sepsis treatment.
作者
夏文芳
李冰玉
林维山
潘舟
邓志敏
张勇刚
XIA Wenfang;LI Bingyu;LIN Weishan;PAN Zhou;DENG Zhimin;ZHANG Yonggang(Department of Intensive Care Unit,Renmin Hospital of Wuhan University,Wuhan 430060,China;The First Clinical College of Wuhan University,Wuhan 430060,China)
出处
《医学综述》
2019年第11期2169-2175,共7页
Medical Recapitulate
基金
国家自然科学基金(81671941)
武汉大学医学部大学生创新实验项目(MS2018013)
关键词
脓毒症
免疫疗法
中医中药治疗
Sepsis
Immunotherapy
Treatment of traditional Chinese medicine
