摘要
目的比较鼻持续气道正压通气(nasal continuous positive airway pressure,NCPAP)和鼻间歇正压通气(neonatal nasal intermittent positive pressure ventilation,NIPPV)对早产儿呼吸窘迫综合征撤机后病情恢复的影响。方法选择2016年1月—2018年1月我院接收的60例早产儿呼吸窘迫综合征患儿,按照随机数字表法分为对照组与试验组,在撤离呼吸机后分别采用NCPAP与NIPPV进行干预,对比两组通气治疗前后pH、PaCO2以及OI;统计两组撤机失败率。结果两组患儿治疗前pH、PaCO2以及OI对比差异均无统计学意义(P> 0.05);在经过不同正压通气后,两组PaCO2、OI水平在通气6 h、24 h后较通气前有明显改善,但组间对比发现,试验组通气6 h、24 h的pH、OI水平明显高于对照组,PaCO2水平低于对照组,差异有统计学意义(P<0.05);试验组患儿撤机失败率明显低于对照组,差异有统计学意义(P <0.05)。结论相比NCPAP,采用NIPPV通气方式有助于改善早产儿呼吸窘迫综合征的血气分析水平,提高撤机成功率,对促进患儿病情恢复意义重大。
Objective To study the impact of nasal continuous positive airway pressure (NCPAP) and neonatal nasal intermittent positive pressure ventilation (NIPPV) in respiratory distress syndrome (RDS) premature infant’s recovery after the ventilator weaning.Methods 60 RDS premature infants treated from January 2016 to January 2018 in our hospital were selected and randomly assigned to control group and test group.After weaning,infants were treated with NCPAP or NIPPV,respectively.The values of pH (potential of hydrogen),PaCO2 (partial pressure of carbon dioxide) and OI (oxygenation index) as well as failed weaning rate were counted.Results Before treatment,there was no significant difference in pre-treatment pH,PaCO2 and OI between the two groups (P > 0.05).After 6 h and 24 h of ventilation,the values of PaCO2,OI for two groups were better than before,but the values of pH and OI in the test group were higher than control group,while the values of PaCO2 were lower than control group (P < 0.05).The failed weaning rate in the test group was significantly lower than control group (P < 0.05).Conclusion Compared with NCPAP,NIPPV can improve the blood gas analysis indicators,increase the successful weaning rate and promote the fast recovery.
作者
张志华
敖桢桢
ZHANG Zhihua;AO Zhenzhen(Neonatology Department,Heyuan Women andChildren’s Hospital and Health Institute,Heyuan Guangdong 517000,China)
出处
《中国卫生标准管理》
2019年第7期57-60,共4页
China Health Standard Management
关键词
鼻持续气道正压通气
鼻间歇正压通气
早产儿
呼吸窘迫综合征
撤机
血气分析
nasal continuous positive airway pressure
neonatal nasal intermittent positive pressure ventilation
premature infant
respiratory distress syndrome
weaning
blood gas analysis
