摘要
为临床深入研究子宫内膜异位症(EMs)的病因、发病机制、治疗药物和预防对策提供合理的大鼠模型。本文对EMs大鼠模型的发病机制、建模方法、优化措施、评价标准以及模型应用等进行综合阐述和比较,研究者可根据实验需要选择合适的建模方法,使其更加贴合实验及临床研究的需要。
In order to establish reliable rat model to study the etiology,pathogenesis and treatment of endometriosis,this article reviewed the literature on the rat model of endometriosis,including the pathogenesis,modeling method,the refinement,evaluation criterion and the application of rat endometriosis model.This review may offer an important reference for choosing animal models to study endometriosis in the future.
作者
纪莲
马铁
刘冬妍
JI Lian;MA Tie;LIU Dong-yan(Department of Medical Research Center;Department of Pathology,Shengjing Hospital,China Medical University,Shenyang 110004,China)
出处
《实验动物与比较医学》
CAS
2019年第1期72-76,共5页
Laboratory Animal and Comparative Medicine
