摘要
目的:分析子痫前期孕妇TG、TC、LDL-C、LDL-C/HDL-C的特征及与不良妊娠结局关系。方法:选取98例子痫前期孕妇,另以医院同期收治的健康妊娠女性中随机抽取98例作为对照组。检测两组的血脂指标,包括总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C),计算血脂比值TC/HDL-C、TG/HDL-C、LDL-C/HDL-C并进行比较。观察PE孕妇的妊娠结局,比较不良妊娠结局孕妇与无不良妊娠结局孕妇的TC、TG、LDL-C、HDL-C、TC/HDL-C、TG/HDL-C、LDL-C/HDL-C,并分析不良妊娠结局的多因素Logistic回归分析。结果:两组血清TC、LDL-C与HDL-C的差异均无统计学意义(P>0.05);PE组血清TG水平显著高于对照组(t=6.556,P<0.05)。PE组TC/HDL-C、TG/HDL-C、LDL-C/HDL-C均显著高于对照组(t=4.723,7.996,5.445,P<0.05)。98例PE孕妇中,不良妊娠结局总发生率为24.48%(24/98)。不良妊娠结局孕妇与无不良妊娠结局孕妇的TC、LDL-C、HDL-C水平的差异无有统计学意义(P>0.05),TG、TC/HDL-C、TG/HDL-C、LDL-C/HDL-C水平的差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,TC/HDL-C、TG/HDLC、LDL-C/HDL-C为不良妊娠结局的影响因素(P<0.05)。结论:PE孕妇的TG、TC/HDL-C、TG/HDLC、LDL-C/HDL-C显著高于对照组,其中TC/HDL-C、TG/HDL-C、LDL-C/HDL-C为PE孕妇不良妊娠结局的影响因素。
Objective:To analyze the characteristics of TG,TC,LDL-C,LDL-C/HDL-C in preeclampsia and its relationship with adverse pregnancy outcomes.Methods:A total of 98 cases of preeclampsia pregnant women were selected,the 98 cases healthy pregnant women of the hospital in the same period were randomly selected as the control group.The lipid levels of the two groups were measured,including total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),and calculated blood lipid ratio TC/HDL-C,TG/HDL-C,LDL-C/HDL-C and were compared between the PE group and the control group.The pregnancy outcome of pregnant women with PE was observed,compare TC,TG,LDL-C,HDL-C,TC/HDL-C,TG/HDL-C,LDL-C/HDL-C in pregnant women with adverse pregnancy outcomes and those without adverse pregnancy outcomes.And analyzed multivariate logistic regression analysis of adverse pregnancy outcomes.Results:There were no significant difference in serum TC,LDL-C and HDL-C between the two groups(P>0.05).The serum TG levels in PE group was significantly higher than that in control group(t=6.556,P<0.05).The TC/HDL-C,TG/HDL-C,and LDL-C/HDL-C in the PE group were significantly higher than those in the control group(t=4.723,7.996,5.445,P<0.05).Among 98 pregnant women with PE,the overall incidence of adverse pregnancy outcomes was 24.48%(24/98).There were no significant difference in the levels of TC,LDL-C and HDL-C between pregnant women with adverse pregnancy outcomes and those without adverse pregnancy outcomes(P>0.05),while the TG、TC/HDL-C、TG/HDL-C、LDL-C/HDL-C levels were statistically significant(P<0.05).The multivariate logistic regression analysis showed that TC/HDL-C,TG/HDL-C,and LDL-C/HDL-C were the influencing factors of adverse pregnancy outcome(P<0.05).Conclusion:The TG,TC/HDL-C,TG/HDL-C,and LDL-C/HDL-C in PE pregnant women were significantly higher than those in the control group,among which TC/HDL-C,TG/HDL-C,LDL-C/HDL-C Influencing factors for adverse pregnancy outcomes in PE pregnan
作者
梁琴
周腊
LIANG Qin;ZHOU La(Weinan Maternal and Child Health Care Hospital,Shaanxi Weinan 714000,China)
出处
《河北医学》
CAS
2018年第10期1707-1711,共5页
Hebei Medicine
基金
陕西省社会发展科技攻关项目
(编号:2015SF116)
关键词
子痫前期
血脂水平
血脂比值
妊娠结局
影响因素
Preeclampsia
Blood lipid levels
Blood lipid ratio
Pregnancy outcomes
Relevance
