摘要
目的分析分层应变技术对2型糖尿病患者左室改变的评估价值。方法选取2015年2月~2017年2月石家庄市第一医院收治的2型糖尿病患者100例纳入糖尿病组,其中男性62例,女性38例,年龄32~62岁,平均年龄(46.2±10.0)岁。另取同期健康体检者100例纳入对照组,男性59例,女性41例,年龄33~64岁,平均年龄(46.1±10.0)岁。应用常规超声心动图测量两组左房内径(LAD)、左室舒张末期内径(LVEDd)、室间隔厚度(IVST)、左室后壁厚度(LVPWT)、相对室壁厚度(RWT)以及左室射血分数(LVEF)水平;计算左室壁18个阶段的内、中、外层心肌的收缩期峰值圆周应变(CS)和收缩期峰值纵向应变(LS)以及整体的分层与全层应变值。结果糖尿病组的空腹血糖与餐后2 h血糖分别为(10.43±1.91)mmol/L、(14.32±1.60)mmol/L,均显著高于对照组的(4.63±0.63)mmol/L、(5.62±0.63)mmol/L,差异均有统计学意义(P均<0.05)。糖尿病组患者的RWT水平为(0.40±0.11),高于对照组的(0.37±0.02),差异有统计学意义(P<0.05)。糖尿病组分层以及整体CS与LS水平分别为(-29.59±6.42)、(-23.91±4.09)、(-20.12±3.17)、(-24.59±3.92)、(-23.98±3.38)、(-21.85±3.18)、(-20.0±2.61)、(-21.17±3.41)均显著高于对照组(-37.88±4.95)、(-30.61±3.52)、(-23.34±2.76)、(-30.45±3.57)、(-26.44±2.62)、(-23.51±2.23)、(-21.35±2.08)、(-23.44±2.57),差异均有统计学意义(P均<0.05)。结论分层应变技术可定量评估2型糖尿病患者左室各层与整体心肌的收缩功能改变,对糖尿病患者左室早期改变评估价值较高。
Objective To analyze the review value of layer strain technology to changes of left ventricle in patients with type 2 diabetes mellitus(T2DM).Methods T2DM patients(n=100,male 62,female 38,aged from 32 to 62 and average age=46.2±10.0)were chosen into T2DM group from the First Hospital of Shijiazhuang City from Feb.2015 to Feb.2017.Meanwhile healthy controls(n=100,male 59,female 41,aged from 33 to 64 and average age=46.1±10.0)were chosen into control group.The left atrial diameter(LAD),left ventricular enddiastolic inner diameter(LVEDd),interventricular septal thickness(IVST),left ventricular posterior wall thickness(LVPWT),relative wall thickness(RWT)and left ventricular ejection fraction(LVEF)were detected by using routine echocardiogram in 2 groups.The peak systolic circumferential strain(CS),peak systolic longitudinal strain(LS),and strain value of whole stratification and full-thickness of inner,medial and outer myocardial layers of 18 segments in left ventricular wall were calculated.Results The level of fasting plasma glucose(FPG)was(10.43±1.91)mmol/L and 2-hour postprandial blood glucose(2-hPBG)was(14.32±1.60)mmol/L in T2DM group,and FPG was(4.63±0.63)mmol/L and 2-hPBG was(5.62±0.63)mmol/L in control group(all P<0.05).RWT level was higher in T2DM group(0.40±0.11)than that in control group(0.37±0.02,P<0.05).The levels of CS and LS of full-thickness and whole stratification were,respectively,(-29.59±6.42),(-23.91±4.09),(-20.12±3.17),(-24.59±3.92),(-23.98±3.38),(-21.85±3.18),(-20.0±2.61),and(-21.17±3.41)in T2DM group,and were,respectively,(-37.88±4.95),(-30.61±3.52),(-23.34±2.76),(-30.45±3.57),(-26.44±2.62),(-23.51±2.23),(-21.35±2.08),and(-23.44±2.57)in control group(all P<0.05).Conclusion Layer strain technology can quantitatively review the changes of systolic function of different layers and whole myocardium of left ventricle in T2DM patients,which has higher value to review on early changes of left ventricle in T2DM patients.
作者
程琦
何玉芳
何鑫
张平格
房勤茂
刘瑛
Cheng Qi;He Yufang;He Xin;Zhang Pingge;Fang Qinmao;Liu Ying(Department of Function,First Hospital of Shijiazhuang City,Shijiazhuang 050010,China)
出处
《中国循证心血管医学杂志》
2018年第7期820-822,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
河北省卫计委重点研究计划(20170981)
关键词
2型糖尿病
分层应变技术
左室改变
超声心动图
评价
Type 2 diabetes mellitus
Layer strain technology
Changes of left ventricle
Echocardiogram
Review
