摘要
目的探讨在急性重症胰腺炎(SAP)治疗中应用大承气汤加味的临床效果。方法方便选择60例SAP患者,并将其分成常规治疗组和大承气汤加味治疗组各30例,患者入院时间范围在2015年8月—2017年12月间,观察两组不同治疗方法下患者胃肠减压和血淀粉酶恢复至正常及住院所用时间,检测两组血淀粉酶、尿淀粉酶及C反应蛋白治疗前后水平,对治疗的有效率进行统计。结果常规治疗组与大承气汤加味组患者胃肠减压的时间分别为(5.11±1.59)d、(3.92±1.27)d(t=3.912,P=0.001);血淀粉酶恢复正常时间分别为(5.44±1.08)d、(3.41±1.41)d(t=7.488,P=0.001);住院所用时间分别为(16.34±4.08)d、(9.33±3.47)d (t=8.733,P=0.001)。治疗后两组血淀粉酶分别是(865±78)U/L、(325±64)U/L(t=3.124,P=0.003);尿淀粉酶分别为(169±31)U/L、(94±26)U/L(t=2.235,P=0.005);C反应蛋白分别为(55±9)U/L、(27±6)U/L(t=1.821,P=0.010)。大承气汤加味组的治疗有效率为93.33%,明显高于常规治疗组的80.00%(χ~2=5.24,P=0.045)。结论对于SAP患者采用大承气汤加味进行治疗,效果显著,推广价值大。
Objective To observe the clinical effect of Dachengqi Decoction in the treatment of acute severe pancreatitis （SAP）. Methods Sixty patients with SAP were convenient enrolled and divided into 30 patients in the conventional treatment group and Dachengqi Decoction treatment group. The hospital admission time ranged from August 2015 to December 2017, and the two groups were observed under different treatment methods. The patient＇s gastrointestinal decompression and blood amylase were restored to normal and hospitalization time. The levels of serum amylase, urinary amylase and C-reactive protein were measured before and after treatment, and the effective rate of treatment was counted. Results The time of gastrointestinal decompression in the conventional treatment group and Dachengqi Decoction group were （5.11±1.59） d, （3.92±1.27） d （t=3.912,P=0.001）, and the blood amylase returned to normal time. They were （5.44± 1.08）d, （3.41±1.41）d （t=7.488 ,P=0.001）, and the time spent in hospitalization was （16.34±4.08）d and （9.33±3.47）d （t=8.733, P=0.001）. After treatment, the blood amylases of the two groups were （865±78） U/L, （325±64） U/L （t=3.124,P=0.003）, and the urinary amylase was （169±31） U/L, （94±26） U/L （t=2.235,P=0.005）; C-reactive protein was （55±9） U/L, （27±6） U/L （t= 1.821 ,P=0.010）. The effective rate of Dachengqi Decoction group was 93.33%, which was significantly higher than that of the conventional treatment group （χ^2=5.24,P=0.045）. Conclusion For the SAP patients, the treatment with Dachengqi Decoction is effective, and the promotion value is great.
作者
吴庆旭
WU Qing-xu(Department of General Surgery,Ganyu Hospital,Lianyungang,Jiangsu Province,222100 China)
出处
《中外医疗》
2018年第26期174-176,共3页
China & Foreign Medical Treatment
关键词
大承气汤加味
急性重症胰腺炎
治疗效果
Daehengqi Decoction
Acute severe panereatitis
Therapeutic effect
