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中药大承气汤联合奥曲肽治疗重症急性胰腺炎临床观察 被引量:6

Clinical Observation of Chinese Medicine Dachengqi Tang Combined with Octreotide for Severe Acute Pancreatitis
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摘要 目的:观察中药大承气汤联合奥曲肽治疗重症急性胰腺炎临床疗效。方法:将纳入的76例重症急性胰腺炎患者按随机数字表法分为2组各38例,2组患者入院后均给予常规治疗,治疗组在常规治疗的基础上给予中药大承气汤联合奥曲肽治疗,对照组在常规治疗的基础上加用奥曲肽治疗,比较2组临床治疗效果。结果:临床疗效总有效率治疗组89.47%,对照组68.42%,2组临床疗效比较,差异有统计学意义(P<0.05);治疗组腹痛消失、腹胀消失、肠鸣音恢复、排气恢复及住院时间均短于对照组,2组间比较,差异均有统计学意义(P<0.05);且2组血清淀粉酶、脂肪酶、血白细胞及急性生理和慢性健康状况评估-Ⅱ(APACHE-Ⅱ)评分均有改善,治疗前后比较,差异均有统计学意义(P<0.05);且治疗组改善情况分别与对照组比较,差异均有统计学意义(P<0.05)。结论:中药大承气汤联合奥曲肽治疗重症胰腺炎临床疗效良好,能缓解患者临床症状,缩短住院时间,值得临床应用。 Objective:To observe the clinical effect of Chinese medicine Dachengqi tang combined with octreotide for severe acute pancreatitis. Methods:Selected 76 patients with severe acute pancreatitis and divided them into two groups being 38 cases in each. The two groups were given routine treatment,and the treatment group was given Chinese medicine Dachengqi tang combined with octreotide in addition, and the control group was given octreotide additionally. Compared clinical effect of the two groups. Results:The total effective rate was 89.47% in the treatment group,and was 68.42% in the control group,the difference being significant(P〈0.05).The time of abdominal pain disappeared and abdominal distension disappeared,recovery time of bowel sounds and venting,and hospitalization of the treatment group were all shorter than those of the control group, the difference being significant(P〈0.05).Scores of blood amylase, lipase,white blood cell,acute physiology and chronic health evaluation Ⅱ(APACHE-Ⅱ) score of the two groups were all improved,and the difference of the improvement of the two groups were significant(P〈0.05). Conclusion:Chinese medicine Dachengqi tang combined with octreotide has good clinical efficacy,and can relieve clinical symptoms of patients,shorten the hospitalization,which is worth of clinical application in treating severe acute pancreatitis.
出处 《新中医》 CAS 2017年第5期57-59,共3页 New Chinese Medicine
关键词 重症急性胰腺炎 大承气汤 奥曲肽 肠鸣音恢复时间 血清淀粉酶 脂肪酶 血白细胞 急性生理和慢性健康状况评估-Ⅱ(APACHE-Ⅱ)评分 Severe acute pancreatitis Dachengqi tang octreotide Recovery time of bowel sounds Blood amylase Lipase White blood cell Acute physiology and chronic health evaluation Ⅱ(APACHE-Ⅱ) score
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