摘要
目的:研究蒙药复方述达格-4对小鼠抗炎镇痛的作用。方法:采用肉芽肿实验法、涂二甲苯至小鼠耳廓使耳朵肿胀法观察抗炎作用,采用腹腔注射醋酸致小鼠扭体法观察镇痛作用。结果:各剂量组与模型组比较,得出蒙药复方述达格-4(150 mg/kg)组能抑制棉球致小鼠肉芽肿的生长,肉芽肿的重量为16.8±0.77mg;抑制二甲苯致小鼠耳肿胀,抑制率26.23%;抑制冰醋酸引起的小鼠扭体反应,抑制率31.45%。结论:蒙药复方述达格-4对小鼠有显著的抗炎镇痛作用。
Objective：To study the anti-inflammatory and analgesic effects of Mongolian medicinecompound Sendeng-4 inmice.Methods：The anti-inflammatoryeffects were observed by the cotton ballgranuloma,the methods of mice ear swelling. The analgesia effects were observed by the methods ofwrithing body.Results：Comparedwithmodel group,Mongolian medicine compound Sendeng-4（150 mg /kg）could inhibit the growth of the cotton granuloma in mice,the weight of granuloma is 16.8±0.77mgand ear swelling induced by dimethylbenzene,inhibition ratio is 26.23%,inhibit the writhing body reac￣tion induced by acetic acid,inhibition ratio is 31.45%.Conclusion：Mongolian medicine compound Sen￣deng-4 has anti-inflammatory and analgesic effects.
出处
《内蒙古医科大学学报》
2018年第3期283-286,共4页
Journal of Inner Mongolia Medical University
基金
自治区级大学生创新创业训练计划项目(201610132002)
内蒙古自治区高等学校"青年科技英才支持计划"青年科技领军人才(NJYT-14-A12)
关键词
复方述达格-4
抗炎
镇痛
Mongolian medicine compound sendeng-4
anti-inflammatory
analgesic
