摘要
目的探讨儿童哮喘在妊娠和婴儿时期的相关因素。方法选取成都市西区医院2015年2月至2017年2月收治的支气管哮喘患儿196例为哮喘组,选取同期进行健康体检的200例正常儿童为对照组。制定统一的调查问卷,采集患儿和母亲的资料进行分析。结果哮喘组和对照组在1分钟Apgar评分、胎龄、胎盘粗糙、分娩方式、新生儿期使用抗生素、母乳喂养时间、新生儿期服用益生菌、孕期使用抗生素、妊娠期高血压和孕早期发热方面的差异均存在统计学意义(χ~2=4.501~41.850,均P<0.05)。经Logistic回归分析显示胎龄、胎盘粗糙、新生儿期使用抗生素、新生儿期服用益生菌、孕期使用抗生素和孕早期发热均是支气管哮喘妊娠和婴儿时期的独立危险因素(χ~2=5.194~17.019,均P<0.05)。结论妊娠和婴儿时期胎龄、胎盘粗糙、新生儿期使用抗生素、新生儿期服用益生菌、孕期使用抗生素和孕早期发热是支气管哮喘的独立危险因素。
Objective To study the related factors of childhood asthma in pregnancy and infancy.Methods Altogether 196 children patients with bronchial asthma admitted in Chengdu Western Hospital from February 2015 to February 2017 were selected as asthma group.A total of 200 normal children receiving physical checkup in the hospital were selected as control group.A unified questionnaire was developed to collect information of children and mothers.Results There were significant differences in 1 min Apgar score,gestational age,placental roughness,mode of delivery,use of antibiotics in neonatal period,breastfeeding time,use of probiotics in neonatal period,use of antibiotics during pregnancy,gestational hypertension and early pregnancy fever between asthma group and control group（χ~2 value ranged 4.501-41.85,all P〈0.05）.Logistic regression analysis showed that gestational age,placental roughness,use of antibiotics in neonatal period,use of probiotics in neonatal period,use of antibiotics during pregnancy and early pregnancy fever were independent risk factors for bronchial asthma in pregnancy and infancy（χ~2 value ranged5.194-17.019,all P〈0.05）.Conclusion Gestational age,placental roughness,use of antibiotics in neonatal period,use of probiotics in neonatal period,use of antibiotics during pregnancy and early pregnancy fever in pregnancy and infancy are independent risk factors for bronchial asthma.
出处
《中国妇幼健康研究》
2017年第12期1739-1741,共3页
Chinese Journal of Woman and Child Health Research
关键词
支气管哮喘
妊娠
婴儿
危险因素
bronchial asthma
pregnancy
infant
risk factors
