摘要
目的 探讨髋部骨折并发下肢静脉血栓栓塞症（VTE）的高危因素,以减少下肢VTE的发生,促进患者早日康复.方法 回顾性分析2016年2月至2017年2月吉林大学中日联谊医院骨科收治的508例髋部骨折患者.通过对患者的年龄、性别、合并系统性疾病、吸烟史、手术时间、是否预防性抗凝、待术时间、骨折部位、麻醉方式、手术方式等进行多因素分析,以分析髋部骨折并发下肢VTE的高危因素.结果 508例髋部骨折患者中有129例发生下肢VTE,发生率为25.4％.多因素Logistic回归分析结果显示：年龄40～59岁（OR 25.986,95％CI 4.552～148.342）及年龄≥60岁（OR 66.672,95％CI 11.458～387.967）、合并系统性疾病≥2种（OR 0.228,95％CI 0.105～0.495）、吸烟（OR 3.070,95％CI 1.647～5.722）、无预防性抗凝（OR 0.069,95％CI 0.030～0.159）、待术时间≥3 d（OR 9.966,95％CI 4.791～20.733）均是髋部骨折并发下肢VTE的重要危险因素.结论 年龄40～59岁及≥60岁、合并系统性疾病≥2种、吸烟、无预防性抗凝、待术时间≥3 d是髋部骨折并发下肢VTE的独立危险因素.
Objective To analyze the risk factors for lower limb venous thromboembolism of patients undergoing hip fractures operation, reduce the incidence of VTE, improve the prognosis of patients. Methods From February 2016 to February 2017, 508 patients with hip fractures were involved in the study from Sino Japanese Union Hospital of Jilin University. The patients were divided into VTE group and VTE-free group. The data were analyzed concerning general clinical information, combined with other systemic diseases, smoking, operation-time, duration from injury to operation, fracture type, anesthetic techniques and so on. The risk factors of VTE were determined using Logistic regression analysis. Results The overall incidence of VTE in this cohort was 25.4% （129/508）. Multi-factor Logistic regression analysis revealed the following risks related to VTE：age 40-59 years（OR 25.986,95%CI 4.552-148.342）and age over 60 years （OR 66.672,95%CI 11.458-387.967 ）, concomitant disease （OR 0.228,95%CI 0.105-0.495 ）, smoking （OR 3.070, 95%CI 1.647-5.722 ）, non-usage of prophylactic anticoagulants（OR 0.069, 95%CI 0.030-0.159）, duration from injury to operation≥3 days（OR 9.966,95%CI 4.791-20.733）. Conclusions Age, presence of concomitant disease, smoking, non-usage of prophylactic anticoagulants, duration from injury to operation are the risk factors for VTE in patients with hip fracture.
出处
《中国实用护理杂志》
2017年第34期2673-2676,共4页
Chinese Journal of Practical Nursing
关键词
髋
骨折
静脉血栓栓塞
危险因素
Hip
Fracture
Venous thromboembolism
Risk factors
