摘要
柯萨奇A组病毒(Coxsackievirus A,CV-A)属肠道病毒,可引起脑膜炎和心肌炎、疱疹性咽峡炎、结膜炎及手足口综合征等多种疾病。近年来,随着以CV-A为主要病原的疫情增多,针对CV-A的研究也引起了更多关注。本文就该组病毒的基本特征、主要致病机制及相关抗病毒药物研究进展进行概述。
Coxsackievirus A(CV-A)is a common virus associated with a number of serious human diseases,including meningitis,myocarditis,herpangina,conjunctivitis and hand,foot and mouth syndrome. In recent years,with the increase of epidemics events with CV-A as the main pathogen,the studies focusing on the CV-A infection have attracted more attention. In this paper,we comprehensively review the basic characteristics,pathogenesis and potential antiviral drugs of CV-A.
作者
申天甜
徐晨
高向东
SHEN Tian-tian XU Chen GAO Xiang-dong(College of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China Beijing Tri-Prime Gene Pharmaceutical Co., Ltd, Beijing 102600, China)
出处
《国际药学研究杂志》
CSCD
北大核心
2017年第6期480-486,共7页
Journal of International Pharmaceutical Research