摘要
(1)目的探讨血糖对冠状动脉狭窄程度及冠状动脉斑块性质的影响。(2)方法收集171例冠状动脉粥样硬化患者的影像及临床资料,根据血糖水平分为Ⅰ组(无血糖异常)、Ⅱ组(葡萄糖调节受损IGR)、Ⅲ组(2型糖尿病T2DM)。比较3组患者冠状动脉狭窄程度及冠状动脉斑块发生率的差异。(3)结果Ⅰ组钙化斑块的发生率较Ⅱ组及Ⅲ组升高,差异有统计学意义(P<0.05);Ⅲ组非钙化斑块的发生率及混合斑块的发生率均较Ⅰ组及Ⅱ组升高,差异有统计学意义(P<0.05);Ⅲ组冠状动脉中度狭窄及重度狭窄的发生率均较Ⅰ组及Ⅱ组升高,差异有统计学意义(P<0.05)。(4)结论随着患者血糖水平的升高,冠状动脉混合斑块及非钙化斑块的发生率升高,钙化斑块的发生率降低,冠状动脉狭窄程度加重。
Objective To explore the correlation between the level of blood glucose and the degree of coronary artery stenosis and coronary artery plaque nature.Methods 171 patients CT coronary angiography diagnosis of coronary atherosclerosis were included in the study, coronary atherosclerosis group, coronary atherosclerosis with impaired glucose regulation group, coronary atherosclerosis with type 2 diabetes mellitus（T2DM） group,and the clinical and imaging data of these patients were collect- ed. We compared the degree of the coronary artery stenosis and the incidence rate of the coronary ar- tery plaques in each group respectively.Results The incidence rate of the calcification plaques in the coronary atherosclerosis group was higher than those groups（ P ~0.05）. The incidence rate of the non --calcification plaques and the incidence rate of the mixed plaques in the T2DM group was higher than those groups（ P 〈05）. The incidence of modarate coronary stenosis and the incidence of severe coronary stenosis among these groups were significant（ P 〈0.05）.Conclusion With the increase of the level of the level of blood glucose, the incidence rate of the mixed and non-calcification plaques increased obviously ,and the coronary artery narrow degree is more serious.
出处
《华北理工大学学报（医学版）》
2017年第3期204-207,212,共5页
Journal of North China University of Science and Technology：Health Sciences Edition
关键词
冠状动脉造影
粥样硬化斑块
冠状动脉狭窄
血糖
Coronary Angiography. Atherosclerotic Plaque.Coronary artery stenosis.Coronary plaques.Blood sugar
