摘要
目的探讨^(99m)Tc-MDP SPECT骨显像结合血清肿瘤相关物质(TAM)对脊柱单发肿瘤良恶性的鉴别诊断意义。方法选取脊柱单发肿瘤患者43例,行^(99m)Tc-MDP SPECT骨显像,同时进行血清肿瘤相关物质(TAM)检测,并于检查完毕后经手术或穿刺获取病理结果,分别观察并比较全身骨显像结果和全身骨显像结合血清肿瘤相关物质(TAM)的检测结果与病理结果的符合情况。结果 43例患者的病理结果中,恶性病变为25例,良性病变为18例;14例^(99m)Tc-MDP SPECT骨显像的图像分析结果与病理结果相符,29例不相符(包括无法明确病变性质);36例99mTc-MDP SPECT骨显像结合血清TAM检测的判定结果与病理结果相符,7例不相符。经配对非参数检验,两者差异有统计学意义(P<0.05)。结论 ^(99m)Tc-MDP SPECT骨显像结合血清TAM检测可作为一个比较有效的鉴别脊柱单发肿瘤良恶性的早期诊断手段。
Objective To explore the value of the99mTc-MDP SPECT bone imaging comined with serum tumor associated material（TAM） in the differential diagnosis of single spinal tumor. Methods 43 patients with single spinal tumor underwent99mTc-MDP SPECT whole body bone imaging and the detection of TAM, then all patients were pathologically diagnosed.Observed and compared the coincidence between the imaging, imaging combined with TAM and pathological diagnosis. Results According to the pathological results,25 patients had bone malignancy, 18 patients had bone benign tumor. According to the results of SPECT imaging, 14 patients were consistent with pathological results. And 36 patients were consistent with the pathological results in the results of SPECT imaging combined with TAM. Conclusion99mTc-MDP SPECT bone imaging combined with TAM may be an effective differential diagnostic method for single spinal tumor.
作者
岳阳平
窦国胜
Yue Yangping Dou Guosheng(Department of Nuclear Medicine,Huizhou Hospital Affiliated to Guangzhou Medical University, Huizhou 516000)
出处
《中国现代医药杂志》
2016年第9期34-36,共3页
Modern Medicine Journal of China
关键词
脊柱肿瘤
放射性核素显像
血清肿瘤相关物质
鉴别诊断
Spinal tumor
Radionuclide imaging
Serum tumor associated material
Differential diagnosis
