摘要
目的分析全身骨显像与单光子发射计算机断层成像(SPECT)/CT显像诊断骨软骨瘤的图像特点,以提高该病影像学特征的认识。方法回顾性分析2015年1月至2020年10月经病理确诊的50例骨软骨瘤患者的全身骨显像与SPECT/CT显像资料,男28例,女22例,年龄6~72岁,总结患者全身骨显像与SPECT/CT融合显像的图像特征。结果单发性骨软骨瘤占78%(39/50),多发性骨软骨瘤占22%(11/50),其中多发者以身体双侧对称受累多见。全身骨显像联合SPECT/CT显像共发现168个病灶,大多数分布在四肢骨(108/168,64.3%),尤其以股骨远端、胫骨近端为主。75%(126/168)病灶呈中-高度放射性摄取浓聚灶,四肢骨病灶多表现为圆形或类圆形摄取,多发病灶主要表现为不规则摄取,肩胛骨及骨盆关节附近多表现为团块状摄取。SPECT/CT显像表现:90.5%(152/168)病灶呈背离关节生长的骨性突起,宽基底与邻近骨质相连,其内骨密度分布不均匀,显像剂在骨质密度增高区呈放射性分布增高或浓集,在囊性低密度区呈放射性分布缺损。结论骨软骨瘤的全身骨显像和SPECT/CT显像具有特征性,对诊断骨软骨瘤具有一定价值。
Objective To analyze the features of osteochondroma on whole-body bone scan and SPECT/CT imaging,so as to improve the recognition of its imaging characteristics.Methods The whole-body bone scan and SPECT/CT imaging data of 50 patients(28 males,22 females,aged:6-72 years)with osteochondroma confirmed by pathology from January 2015 to October 2020 were retrospectively analyzed.The whole-body bone scan combined with SPECT/CT fusion imaging and imaging features were retrospectively analyzed.Results Single osteochondroma accounted for 78%(39/50)and multiple osteochondroma accounted for 22%(11/50),among which bilateral symmetrical involvement was the most common.A total of 168 lesions were found by whole-body bone scan and SPECT/CT imaging,most of which were distributed in the extremities(108/168,64.3%),especially in the distal femur and proximal tibia.75%(126/168)of the lesions showed moderate to high radiation uptake concentration foci,the four limb bone lesions were mostly round or quasi-round uptake,the multiple lesions were mainly irregular uptake,and the mass uptake near the scapula and pelvic joints was mostly observed.SPECT/CT imaging findings:90.5%(152/168)lesions were found bony protrusion that diverts from the growth of joints,the wide base was connected with adjacent bone,and the distribution of bone density was not uniform,as well as the imaging agent showed increased or concentrated radioactive distribution in the increased bone density area,and radioactive distribution defect in the low cystic density area.Conclusion The characteristics of osteochondroma on whole-body bone scan combined with SPECT/CT imaging have certain value for the diagnosis of osteochondroma.
作者
欧蕾
吴骥
龚维冬
吴俊豪
江国豪
张春银
OU Lei;WU Ji;GONG Weidong(Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province,The Affiliated Hospital of Southwest Medical University,Academician(Expert)Workstation of Sichuan Province,Luzhou,Sichuan Province 646000,P.R.China)
出处
《临床放射学杂志》
北大核心
2021年第8期1568-1572,共5页
Journal of Clinical Radiology
基金
四川省重点实验室建设基金项目(编号:2018JPT0023)。