摘要
目的对比地氟醚与七氟醚在子宫外产时手术麻醉应用效果。方法纳入2015年4月-2016年10月收治的66例行子宫外产时手术患者作为本组研究对象,按照维持麻醉用药差异,分为A组与B组各33例,A组使用地氟醚,B组使用七氟醚,比较两组不同时间点患者NTI、MAP、HR及胎儿HR、FS与EF。结果 t_3、t_4时间点,A组患者NTI明显高于B组(P<0.05);t1时间点,B组MAP明显低于A组(P<0.05);t_1、t_2时间点,B组HR明显高于A组(P<0.05);t_0~t_1时段,两组MAP明显减小,且HR显著增加(P<0.05);Ft_2、Ft_3时间点,A组胎儿SF、EF均明显小于B组,而HR明显大于B组(P<0.05)。结论子宫外产手术过程中,相对于地氟醚,七氟醚可对胎儿心功能产生明显抑制作用,并且七氟醚存在麻醉深度不足的缺点,而地氟醚可减少血管活性药(升压药)的使用量,故地氟醚对子宫外产术麻醉应用价值更高。
Objective To compare the application effect of desflurane and sevoflurane in anesthesia of the ex - utero intrapartum treatment. Methods From April 2015 to October 2016, 66 patients receiving ex - utero intrapartum treatment in our hospital were divided into group A （ n = 33 ） and group B （ n = 33 ） according to different medication for maintaining anes- thesia. Group A was treated with desflurane while group B was treated with sevoflurane. The NTI, MAP, HR and fetal HR, FS and EF were compared between the two groups at different time points. Results At t3 and t4, NTI of group A was signifi- cantly higher than that of group B （ P 〈 0.05 ）. At tl, MAP of group B was significantly lower than that group A （ P 〈 0. 05 ）, and at t1 , t2 , HR of group B were significantly higher than those of group A （ P 〈 O. 05 ）. to - tI , MAP decreased significant- ly while HR increased significantly （ P 〈 0. 05 ）. Ft2 and Ft3 , fetal HR, FS and EF in group A were significantly lower while HR was significantly higher than those in group B （ P 〈 0. 05 ）. Conclusion During the ex - utero intrapartum treatment, compared with sevoflurane, desflurane can obviously inhibit fetal cardiac function. Sevoflurane has the disadvantage of inade- quate depth of anesthesia while desflurane can reduce the dosage of vasoactive drugs （ pressor agents）. Therefore, desflurane is recommended.
出处
《现代医院》
2017年第2期277-279,共3页
Modern Hospitals
关键词
地氟醚
七氟醚
子宫外产
手术麻醉
应用
Desflurane
Sevoflurane
Ex-utero Intrapartum Treatment
Anesthesia
Application
