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滴定法预测肝素-鱼精蛋白量减少体外循环术后出血 被引量:4

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摘要 出血是心脏术后患者常见并发症之一。两种滴定法预测鱼精蛋白的用量均能够减少术后出血,但依赖于对血容量的正确估计。(1)根据滴定结果绘制肝素和鱼精蛋白剂量-反应曲线,从而计算鱼精蛋白需要量;(2)使用系列鱼精蛋白梯度杯绘制肝素-鱼精蛋白滴定结果曲线,从而直接读出鱼精蛋白的使用量。如心功能异常导致患者血容量变化,可在第一次滴定后进行第二次滴定实验,再根据这一实验结果补充鱼精蛋白。后者对于瓣膜疾病导致的患者血容量增高尤为适用。
出处 《中国胸心血管外科临床杂志》 CAS 2013年第6期723-724,共2页 Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
基金 国家自然科学基金资助项目(30872455)
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参考文献12

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二级参考文献16

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