摘要
目的：分析炎症性肠病（ IBD）住院患者营养风险与临床结局之间的关系；探讨IBD住院患者发生营养风险的相关因素，为进一步研究和预防、治疗炎症性肠病患者的营养不良提供理论及实践依据。方法选择2014年1—7月在苏州大学附属第三医院、南京医科大学附属常州二院和南京中医药大学常州附属医院消化内科住院的IBD患者93例作为研究对象。入院后取得患者知情同意，完成病例资料的收集，并使用营养风险筛查2002（ NRS2002）对患者进行营养风险筛查。结果有营养风险组的住院天数、医疗费用高于无营养风险组，差异具有统计学意义（ P〈0.05）；将IBD住院患者营养风险作为因变量，其他可能与营养风险相关的变量作为自变量进行二元Logistic回归分析，结果显示：性别、诊断、疾病严重程度是IBD住院患者发生营养风险的独立危险因素（P〈0.05），即女性患者营养风险发生率高于男性；克罗恩病（ CD）患者营养风险发生率高于溃疡性结肠炎（ UC）患者；疾病越严重，营养风险发生率越高。而营养风险发生率与年龄、病程无关（ P〉0.05）。结论营养风险可预测临床结局，性别、诊断、疾病严重程度是IBD住院患者发生营养风险的独立危险因素。
Objective To explore the relationship between nutritional risk and clinical outcome in hospitalized patients with inflammatory bowel disease （ IBD ）; to analyze the factors influencing the nutritional risk of IBD patients, so that to provide theoretical and practical basis for further study, prevention and treatment of the malnutrition in IBD patients. Methods A total of 93 hospitalized patients with IBD at gastroenterology department in the Third Affiliated Hospital of Soochow University, Changzhou Second Hospital affiliated to Nanjing Medical University and Changzhou Hospital affiliated to Nanjing University of Traditional Chinese Medicine from January to July in 2014 were enrolled into the study. Informed consent forms were signed and case datum of patients were collected within 24 hours after hospitalization, and patients′nutritional status were completed with Nutritional Risk Screening 2002.Results The hospitalization duration and medical expenses of group with nutritional risk were higher than that group without nutritional risk （ P〈0.05）;If we regarded the nutritional risk of hospitalized patients with IBD as the dependent variable, and other variables which might be associated with nutritional risk as independent variables, then conducted a binary logistic regression analysis. The results showed that： gender, diagnosis and disease severity were the independent risk factors of the nutritional risk of hospitalized patients with IBD（P〈0.05）, which means that women′s nutritional risk was higher than men;the nutritional risk of Crohn disease （ CD） was higher than that of ulcerative colitis （ UC ）; the more serious of the disease, the higher incidence of nutritional risk; but nutritional risk had nothing to do with age and course of disease（P〉0.05）.Conclusions Nutritional risk can predict clinical outcomes; gender, diagnosis and disease severity are independent risk factors of the nutritional risk of hospitalized patients with IBD except age and course of disease.
出处
《中华现代护理杂志》
2016年第26期3749-3752,共4页
Chinese Journal of Modern Nursing
关键词
炎症性肠病
营养风险
临床结局
影响因素
Inflammatory bowel disease
Nutritional risk
Clinical outcome
Influencing factors
