摘要
目的:分析老年炎症性肠病患者的生存质量及其影响因素.方法:选取2012-01/2014-01中国人民解放军154医院接收治疗的老年炎症性肠病患者68例,其中包括24例溃疡性结肠炎(ulcerative colitis,UC)患者,以及44例克罗恩病(Crohn's disease,CD)患者.同时选取68例健康者为对照组.应用中文版SF-36量表,以自评法对68例老年炎症性肠病患者的生存质量进行调查,并将调查结果中8个维度得分与对照组进行比较.通过多元逐步回归分析对影响老年炎症性肠病的相关因素进行分析.结果:观察组患者在躯体角色、总体健康、机体疼痛、情感角色、社会功能5个维度的得分显著低于对照组患者,比较两组间差异具有统计学意义(P<0.05),观察组患者心理卫生、活力2个维度的得分显著高于对照组患者,比较两组间差异不具有统计学意义(P>0.05).UC患者与CD患者的生存质量的8个维度得分均无统计学意义(P>0.05).患者的疾病活动指数、年龄、病情自评与生存质量得分呈负向影响,患者的经济状况与生存质量得分呈正向影响.结论:老年炎症性肠病患者的生存质量显著低于健康人群,严格控制患者的疾病活动指数,加强综合干预,能够显著提高患者的生存质量.
AIM：To investigate the quality of life in elderly patients with inflammatory bowel disease（IBD）and to identify factors influencing the quality of life.METHODS：Sixty-eight elderly patients with inflammatory bowel disease treated at the 154 th Central Hospital of Chinese PLA from January2012 to January 2014,including 24 ulcerative colitis（UC） patients and 44 Crohn’s disease（CD） patients,were included in a study group.Sixty-eight healthy volunteers comprised a control group.The Chinese version of the SF-36 scale was used to assess the quality of life.IBD-related factors that may affect the quality of life were analyzed by multivariate regression analysis.RESULTS：The scores of physical,general health,body pain,emotional role,and social functioning were significantly lower in the study group than in the control group（P 〈0.05）.The scores of mental health and vitality were higher in the study group than in the control group,but the differences were not statistically significant（P 〉 0.05）.The scores of all the eight dimensions did not differ significantly between UC and CD patients（P〉 0.05）.The patient’s disease activity index,age,and condition had a negative impact on the quality of life,while economic status had a positive effect.CONCLUSION：The quality of life in elderly patients with inflammatory bowel disease is significantly lower than in healthy people,and strict control of the patient’s disease activity index and strengthening the comprehensive intervention can significantly improve the quality of life of patients.
出处
《世界华人消化杂志》
CAS
2015年第5期823-827,共5页
World Chinese Journal of Digestology
关键词
老年
炎症性肠病
生存质量
影响因素
Elderly
Inflammatory bowel disease
Quality of life
Factors
